Project / Program Title:
<ul> <li>AP26198945 Development of mineral sorbents and their therapeutic efficacy in mycotoxicosis of birds.</li> </ul>

Basic Information

Name of the priority direction of science development, for which the application is submitted. “Sustainable development of agro-industrial complex”.

Name of the specialized scientific direction for which the application is submitted. Veterinary science.

Project Manager: Nurgul Sarsenbekovna Montayeva – PhD Doctor, Associate Professor

Estimated start and completion date of the project, its duration in months. Start date: January 1, 2025, end date December 31, 2027. Duration 36 months.

Requested amount of grant financing (for the whole project implementation period and by year, in tenge). For the whole term – 111,872,484 tenge (one hundred and eleven million eight hundred and seventy-two thousand four hundred and eighty-four tenge). Including for:

2025 – 36,011,684 (thirty-six million eleven thousand six hundred eighty-four) tenge;

2026 – 36,965,910 (thirty-six million eleven thousand six hundred eighty-four) tenge;

2027 – 38 894 890 (thirty-eight million eight hundred ninety-four thousand eight hundred ninety-four) tenge.

Project / Program Tasks
  • Project Objectives
  • To achieve the project goal, the following interrelated tasks will be solved:
  1. Comprehensive studies of the composition and properties of siliceous rock-opoka and bentonite clay
  • Description of the task: to conduct studies of the chemical and mineralogical composition of siliceous rock (opoka) and bentonite clay of the West Kazakhstan deposit. To study the porous structure, specific surface, pore size, density, as well as the presence of micropores, macropores and mesopores.
  • Direction: This task is aimed at determining the physicochemical characteristics of materials, which will confirm their suitability for use as sorbents.
  1. Development of the composition and production technology of the sorbent
  • Description of the task: to optimize the composition of the mineral sorbent to ensure maximum sorption activity and develop a technology for its production.
  • Direction: The task is aimed at creating an effective sorbent capable of adsorbing toxic substances and improving production processes in agriculture.
  1. Evaluation of the sorption properties of the sorbent
  • Task description: to evaluate the adsorption properties of the developed sorbent in relation to mycotoxins common in the feed base of farms in Western Kazakhstan.
  • Direction: The task is aimed at studying the effectiveness of the sorbent, which will confirm its applicability for agriculture.
  1. Toxicological studies of the sorbent safety
  • Task description: to conduct a toxicological assessment of siliceous rock and bentonite clay to confirm their safety when used in feed additives.
  • Direction: The task is aimed at confirming the harmlessness of the sorbent for animals and eliminating possible negative effects.
  1. Evaluation of the therapeutic effectiveness of the sorbent
  • Task description: to conduct an experimental study on laying hens with mycotoxicosis, studying the effect of the sorbent on their clinical, hematological and biochemical parameters.
  • Direction: The task is aimed at confirming the effectiveness of the sorbent in improving the health and productivity of birds.
  1. Veterinary and sanitary examination of products
  • Description of the task: to study the effect of the sorbent on the quality of laying hens' eggs and to conduct an examination of their compliance with sanitary standards.
  • Direction: The task is aimed at confirming the safety and quality of products when using the sorbent in feed.
Achieved Results and Novelty
  • Scientific novelty and significance of the project
  • 1) Prerequisites for the development of the project.
  • The scientific direction of the project's scientific director is the development of new bioactive mineral feed additives with therapeutic and prophylactic action and sorbents for veterinary medicine based on the natural raw material resources of Kazakhstan.
  • In the direction of the research, the director and performers have a significant backlog of scientific and experimental work, which has a positive impact on achieving the expected results of the project. The following patents were obtained:
  • 1 Montaeva N.S. Patent for Utility Model No. 5262 "Method for Obtaining a Combined Mineral Feed Additive with a Therapeutic and Prophylactic Action for Farm Animals", 2020
  • 2 Montaeva N.S., Nametov A.M., Makhimova Zh.N. Patent for invention No. 36336 "Method for producing composite mineral feed additive for poultry", 2023.
  • 3 Application for patent No. 2024/0267.1 "Method for producing mineral modified sorbent for veterinary medicine" has been filed.
  • These patents and preliminary results prove the novelty and relevance of the project, which will replace imported sorbents used in poultry farms in Kazakhstan.
Expected Results
  • Expected results.
  • 1 The study will provide detailed information on the chemical composition and physical characteristics of the starting materials, which will help identify their suitability for sorbent production and determine the parameters that affect its effectiveness.
  • 2 The optimal sorbent composition and production technology will be developed, which will ensure high sorbent efficiency at minimal cost. This will also make it possible to obtain a product with specified sorption properties, stability and safety.
  • 3 It is expected that data will be obtained on the sorption properties of the developed sorbent, including its ability to adsorb various substances. The results will help select the most effective sorbent for specific tasks and operating conditions.
  • 4 Based on toxicological studies, the sorbent's safety for humans and animals will be confirmed, which will allow it to be used without risk to health in various fields, including medical and veterinary use.
  • 5 As a result of clinical and laboratory tests, the therapeutic effectiveness of the sorbent will be confirmed, and optimal dosages and application regimens will be determined to achieve maximum therapeutic results.
  • 6 Based on the results of the veterinary and sanitary examination, the sorbent's compliance with sanitary and hygienic standards and safety requirements will be confirmed, which will allow the product to be introduced to the market for use in veterinary medicine.
  • 7 The following types of equipment will be used within the project, which will be purchased and used for research:
  1. It is expected that the following articles will be published as a result of the project implementation:
  • - The following will be published: at least 2 (two) articles and (or) reviews in peer-reviewed scientific journals indexed in the Science Citation Index Expanded and included in the 1st (first) and (or) 2nd (second) quartile by impact factor in the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 65 (sixty-five);
  • - at least 2 (two) articles or reviews in a peer-reviewed foreign or domestic publication recommended by the Committee on Scientific and Technical Regulation and Supervision of Scientific Research;
  • One of the articles must be in the category - multidisciplinary (multidisciplinary or interdisciplinary practical application) on the tasks of enterprises from the real sector of the economy of Kazakhstan, and the project results must include design documentation prepared according to the Unified System for Design Documentation. 9. One (1) PhD or doctor of science (with a dissertation topic corresponding to the project topic) will be prepared.
List of Project Publications
  • Information on the main publications of the research group related to the topic of the project:
  1. Montayeva, N., Montayev, S., Montayeva, A. Bioactive Mineral Feed Additive for Poultry: Therapeutic and Preventive Effects on Haematological Parameters in Chickens // Evergreen. - 2024.-Vol.11. Iss. 2. - Р. 984-992. DOI:https://doi.org/10.5109/7183380. Quartile Q-2. Percentile 56.
  2. Montayeva, N., Montayev, S., Montayeva, A. Treatment of functional disorders of gastrointestinal tract of calves with complex phytomineral preparation // Scientific Horizons, 2024, 27(8), страницы 47–587. DOI:  https://doi.org/10.48077/scihor8.2024.47. Quartile Q-3. Percentile 36.
  3. Montayeva N. S., Montayev S. A., Montayeva A. S. Studies of Montmorillonitic (Bentonite) Clay of Western Kazakhstan as a Therapeutic Mineral Feed Additive for Animals and Poultry //Agricultural Research. – 2022. – С. 1-6. DOI:2174/2772574X14666221227161809Quartile Q-2. Percentile 67.
  4. Montayeva N., Montayev S., Svotina M. Veterinary medicine based on montmorillonite clay from Western Kazakhstan for the treatment and prevention of infectious diseases in farm animals //Scientia Agropecuaria. – 2024. – Т. 15. – №. 4. – С. 495-502. DOI: http://dx.doi.org/10.17268/sci.agropecu.2024.036. Quartile Q-1. Percentile 75.
  5. 5. Montayeva N. S. Evaluation of toxiological indicators of monthmorrillonite clay for the purpose of using them as alumosilicate sobent against the negative effect of mycotoxins on the body of animals and birds. Наука и образование - № 1-1 (62) 2021. – С.70-76. (КОКНВО МНВО РК). https://nauka.wkau.kz/index.php/gbj/issue/view/27/26
  6. 6. Montayeva N.S., Taiguzin R.S., Abdrakhmanova D.A., Svotina M.A. Research of quail meat for the presence of heavy metals and pesticides when adding a mineral feed additive to their diet. Science and education- № 4 (65) 2021. –С.3-9. (КОКНВО МНВО РК). https://doi.org/10.52578/2305-9397-2021-1-4-3-9
  7. 7. Montayeva N.S., Abdrakhmanova D.A., Svotina M.A. Research of the chemical composition of quail meat when adding a mineral feed additive to their diet. Science and education- - № 3(68) 2022. –С.12-19. (КОКНВО МНВО РК). https://ojs.wkau.kz/index.php/gbj/article/view/921/388
  8. Montayeva N.S. Nagimova G.Kh., Nurzhanova F.Kh. Toxicological assessment of Opoka mineral feed mixture for use in veterinary medicine. Science and Education", Vol. №-1(74) Ural, 2024. - S. 174-184. (KOKNVO MNVO RK). https://ojs.wkau.kz/index.php/gbj/article/view/1953/1065
  9. Montayeva N.S Nagimova G.Kh, Kereev A.K Biochemical blood parameters of broiler chickens when using a siliceous rock additive-apoka in feeding. «Science of knowledge», - No2-1(75) Oral, 2024 ж. – S. 296–303. (KOKNWO MNWO RK). DOI: 2305-9397-2024-2-1-298-305. https://rep.wkau.kz/bitstream/123456789/3408/1/6315.pdf
  10. Montaeva N.S., Nametov A.M., Montaev S.A. Prospects for the creation of natural modified mineral sorbents for veterinary medicine against mycotoxins. «Science of knowledge»,- №-2-1(75) Орал, 2024 ж. – С. 191-203. (КОКНВО МНВО РК). DOI: 10.52578/2305-9397-2024-2-1-191-205. https://rep.wkau.kz/bitstream/123456789/3408/1/6315.pdf
  •  

 

 

📚 Loading…