Name of the project / program topic: AP23490604 «Canines contribute to infectious and parasitic disease transmission, posing risks to animals and humans in metropolitan areas»

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex

The name of the specialized scientific research area:

Veterinary medicine

Scientific director of the project/program: Nametov Askar - doctor of veterinary sciences, professor, academician of the National academy of sciences of the RK.

The implementation period, its duration in months. 01.01.2024 – 12.31.2026 year, duration 36 months.

The total amount of funding, and by year: 120000,0,0 thousand tenge,

2024 – 340000,0 thousand tenge.;

2025 – 43000,0 thousand tenge.;

2026 – 43000,0 thousand tenge.

Objects of research, development or design:

dogs

The purpose of the project / program:

Monitoring of dogs living within the megalopolis, a factor in the spread of dangerous infectious and parasitic diseases and the development of safety measures for humans and animals.

Project / program objectives:

1. Determination of the prevalence of infectious and parasitic diseases, as well as aggressive behavior of dogs based on statistical data for the last 5 years.

2. The study of infection with infectious and parasitic diseases in dogs in different areas of the metropolis.

3. The study of the behavior and aggressiveness of dogs, the causes of aggression and the development of measures to reduce it.

4. Development of a monitoring algorithm that includes comprehensive measures and prevention of infections and infestations in dogs.

5. Development of recommendations for regulating the number of dogs in the metropolis and automation of control and accounting based on a software product.

The results obtained and the novelty: (no more than 200 words)

To achieve this goal, an analysis of the reports of the Uralsk Veterinary Inspectorate and the data of the Ural City Sanitary and Epidemiological Control RGU for the period 2020-2024 was conducted. Diagnostics of animal infestation with parasitic diseases was carried out in the «Zhardem vet» veterinary clinic of the Zhangir Khan West Kazakhstan agrarian and technical university using helmintho-ovoscopic examination of feces according to Fülleborn and complete helminthological autopsy according to K.I. Skryabin. According to the «Uralsk veterinary inspectorate and the «Ural City Sanitary and Epidemiological Control»  RGU, over the past 5 years (2020-2024), 5,719 cases of attacks and bites of people by dogs and 2 cases of rabies in dogs have been registered. According to the State Institution "Veterinary Department of the West Kazakhstan Region", 127,480 dogs were vaccinated against rabies in Uralsk in 2019-2024. The epizootic situation for parasitic diseases of dogs in urban areas is quite tense. During the examination of dogs, eight types of helminths were found, belonging to the class, trematode, cestode and nematode. Ectoparasites such as notoedrosis, sarcoptosis, otodectosis, demodicosis are often found. The widespread distribution of parasitoses in dogs is due to the increase in the population of stray dogs.

Novelty Ensuring the safety of the population from socially significant diseases in the conditions of a megalopolis

Expected results:

1. The analysis of the prevalence of infectious and parasitic diseases, as well as aggressive behavior of dogs in the metropolis will be carried out.

2. The infestation of dogs with pathogens of infectious and parasitic diseases in different areas of the metropolis will be determined.

3. The behavior and aggressiveness of dogs, the causes of aggression will be studied and measures to reduce it will be developed.

4. A monitoring algorithm will be developed that includes comprehensive measures and prevention of infections and infestations in dogs.

5. Recommendations will be developed for regulating the number of dogs in the metropolis and automation of control and accounting based on a software product.

6. Within the framework of the project, 2 articles will be published in peer-reviewed scientific publications indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 50 (fifty) and 1 article in a peer-reviewed foreign or domestic publication recommended by the CQAFSHE.

Degree of implementation: no

List of published works within the framework of the project: (with indication of DOI, ISBN) 

Кармалиев Р. С., Кадралиева Б. Т., Наметов А.М., Мурзабаев К. Е., Душаева Л. Ж., Орынханов К. А., Габдуллин Д. Е. Мониторинг распространенности инфекционных и паразитарных болезней и агрессивного поведения собак в Уральске // Ғылым және білім. 2024. № 3-1 (76) С. 193-202 DOI 10.52578/2305-9397-2024-3-1-193-202

Name of the project / program topic: AP19679003 «Development of the technology of watering with desalination of mineralized groundwater by filtration using natural non-carbon modified sorbents»

The name of the priority area of science development for which the application is submitted 2. Rational use of water resources, flora and fauna, ecology

The name of the specialized scientific research area: 2.1 Research of current problems of conservation and management of water resources

Scientific director of the project/program: Montaev Sarsenbek, doctor of technical sciences, professor

The implementation period, its duration in months. 01.02.2023 - 31.12.2025 year, duration 35 month.         

The total amount of funding, and by year: 78 103, 5956 thousand tenge,

2023 year – 24 888,870 thousand tenge;

2024 year – 25 611,470 thousand tenge;

2025 year – 27 603,2556 thousand tenge.

Objects of research, development or design: Siliceous rocks - opoka of Western Kazakhstan and mineralized underground waters for purification and desalination by filtration

The purpose of the project / program: is the development of a technology for watering pasture lands by desalinating mineralized groundwater through filtration in modular bulk filter units using modified natural non-carbon sorbents based on siliceous rock – opoka from the West Kazakhstan deposit – as filter components.

Project / program objectives:

- laboratory studies on the development of various compositions and process parameters for obtaining modified non-carbon sorbents based on siliceous rock - opoka of Western Kazakhstan for purification and desalination of mineralized groundwater by filtration, zoning of the region's territory by the degree of waterlogging and the presence of groundwater with varying degrees of mineralization (task I);

- development of an experimental sample of a Modular installation in the form of a bulk filter with filtering components based on modified siliceous rock - opoka for desalination of mineralized groundwater, its installation, assembly and adjustment at a transhumance site for pasture irrigation (task II);

- scientific justification for the use of a Modular installation in the form of a bulk filter with filtering components based on modified siliceous rock - opoka for desalination of mineralized groundwater for pasture irrigation in the dry steppe zone of Western Kazakhstan (task III).

The results obtained and the novelty:

Various compositions of sorbents based on siliceous rock - opoka of Western Kazakhstan have been developed for purification and desalination of mineralized groundwater. The developed compositions are distinguished by high specific surface area (the total surface area of ​​the sorbent samples is 0.04856 m2 / g) and porosity. The developed sorbents mainly contain mesopores (from 2 to 50 nm), and the largest number of pores have a size of less than 10 nm. High purification and desalination of water is based on the presence of labyrinthine mesopores, which ensures high filtration efficiency and promotes maximum absorption of dissolved mineral salts by the surface of siliceous rock grains - opoka and modifying components.

Expected results:

1) 3 (three) articles will be published in peer-reviewed scientific journals indexed in the Science Citation Index Expanded of the Web of Science database or having a CiteScore percentile in the Scopus database of at least 35 (thirty-five), as well as at least 3 (three) articles in a peer-reviewed foreign or domestic publication recommended by the KOKSNVO.

2) presentations at conferences, reports at seminars and meetings at various levels;

3) searches for the patentability of scientific results will be conducted in the domestic patent office and an application for a patent for a utility model will be filed.

4) During the implementation of the project, it is expected to obtain a scientific effect consisting in the creation of a modular installation in the form of a bulk filter for the purification and desalination of mineralized groundwater for irrigation of pastures of distant-pasture livestock in low-water areas.

The socio-economic effect of the expected results is to provide low-water areas of distant-pasture livestock farming with the technology of irrigation based on desalination of mineralized underground waters on a modular installation in the form of a bulk filter.

5) The research results can be applied by various consumers, including design organizations, agricultural production management structures, akimats, agricultural production entities engaged in distant-pasture livestock farming. The developed technological solutions can be commercialized.

6) The target consumers of scientific results are individuals and legal entities engaged in livestock farming.

7) The work contains certain risks, since it has been practically not studied and is not scientifically substantiated. Therefore, with the expected result, the planned work can affect the development of science and technology.

8) Dissemination of the results of the work among interested parties through publications, press appearances, television and radio broadcasts, conferences and public defenses.

Degree of implementation: Work on the project began in 2023 and is at the initial stage of implementation. The results of the developments will be implemented in the conditions of peasant farms engaged in livestock farming and in need of purification and desalination of underground mineralized waters.

List of published works within the framework of the project:

1 Montayev S.A., Onayev M.K., Denizbayev S.E., Ryskaliev M.Zh., Ozhanov G.S. Structural features of opoka of Western Kazakhstan, proposed as natural non-carbon modified sorbents for desalination of mineralized groundwater of pasture lands // Science and education. Uralsk, 2023. N3-2 (72) 202. – P.267-276. DOI 10.52578/2305-9397-2023-3-2-267-276.

• M.Zh. Rysksliyev, S.Denizbayev Sorption Treatment and Desalination of Mineralized Water Using Opoka to Reduce Hardness and Chloride Content // International Journal of Design and Nature and Ecodynamics (ISSN: 1755-7437). -  2024. - Vol.19 (5). – Р.1733-1740. DOI: https://doi.org/10.18280/ijdne.190527
• S.Denizbayev, S.Sakhipova Hydrochemical Characteristics of Groundwater in Northwestern Kazakhstan Aquifers: Implications for Livestock Water Supply // International Journal of Design and Nature and Ecodynamics. – 2024. - Vol.19 (4). – P.1327-1340. DOI 10.18280/ijdne.190425

4 Montayev S.A., Onayev M.K., Ryskaliev M.Zh., Begaliyeva R.S., Denizbayev S.E. Technology of preparation of water-resistant mineral sorbent based on modified siliceous rock – opoka of Western Kazakhstan and development of modular laboratory unit for desalination of mineralized groundwater // Science and education. Uralsk, 2024. N3-2 (76) 2024. – P. 47-63. DOI 10.52578/2305-9397-2024-3-2-47-64.

Name of the project / program topic: BR21882180 "Development of an environmentally safe antiseptic drug based on natural substances and compounds for use in veterinary medicine" Subsection: "Study of antimicrobial, antiparasitic activity and properties of a complex herbal preparation based on wormwood in veterinary medicine in Western Kazakhstan"

The name of the priority area of science development for which the application is submitted Rational use of natural resources, flora and fauna, ecology;.

The name of the specialized scientific research area: Conservation and rational use of the animal and plant world.

Scientific director of the project/program: Terletskaya Nina - candidate of biological sciences, associate professor Head of the subsection: Karmaliev Rashid - doctor of veterinary sciences, associate professor.

The implementation period, its duration in months. 09/01/2023 - 12/31/2025 year, duration 28 months.

The total amount of funding, and by year: 47 000, 0 thousand tenge,

2023 – 10 000,0 thousand tenge;

2024 – 15 000,0 thousand tenge;

2025 – 22 000,0 thousand tenge.

Objects of research, development or design: Artemisia absinthium, Bídens tripartíta, Chelidónium május, Hypéricum perforátum, agricultural and laboratory animals.

The purpose of the project / program: Study of antimicrobial, antiparasitic activity and properties of a complex herbal preparation based on wormwood and other plants in veterinary medicine in Western Kazakhstan

Project / program objectives:

1. To study the antimicrobial activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan.

2. To study the anthelmintic activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan.

3. To study the acaricidal activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan.

4. To study the effect of a complex herbal preparation on clinical, hematological and biochemical parameters of the animal body (clinical, hematological, biochemical studies);

5. To study the effect of a complex herbal preparation on nonspecific immunity factors in animals (humoral and cellular immunity factors);

6. To study some toxicological (cumulation, LD50) and allergic properties of a complex herbal preparation.

7. To study possible pathoanatomical and histological changes in the animal body after the application of a complex herbal preparation

The results obtained and the novelty: (no more than 200 words)

During the reporting period, as a result of the conducted research: it was determined that the complex herbal preparation No. 1 and No. 2 have antimicrobial and wound healing properties. After their application, the general clinical parameters of the animal body are within the normal range. Hematological and biochemical parameters of animal blood come to the norm on the 17th day after the application of complex herbal preparation No. 1 and on the 19th day - complex herbal preparation No. 2. Complex herbal preparations No. 1 and No. 2 have antihelminthic properties against Moniezia (Moniezia spp.) and strongylate of the sheep digestive tract (Strongylata spp.) when administered orally in an in vivo critical test. Hematological (hemoglobin, erythrocytes, leukocytes, platelets, hemotocrit, thrombocrit) and biochemical (total protein, albumins, α –, β-, γ –globulins) blood parameters of sheep with oral administration of complex herbal preparations No. 1 and No. 2, after 1 to 21 days were within the physiological norm, pathological changes No animal blood was observed.

Novelty: Replacement of chemical antibiotics with herbal preparations with antibacterial and antiparasitic effects.

Expected results:

1. The antimicrobial activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan will be studied.

2. The anthelmintic activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan will be studied.

3. The acaricidal activity in veterinary medicine of a complex herbal preparation in the conditions of Western Kazakhstan will be studied.

4. The effect of a complex herbal preparation on clinical, hematological, biochemical parameters of the animal body (clinical, hematological, biochemical studies) will be studied;

5. The effect of a complex herbal preparation on nonspecific immunity factors in animals (humoral and cellular immunity factors) will be studied;

6. Some toxicological (cumulation, LD50) and allergic properties of a complex herbal preparation will be studied.

7. pathoanatomic and histological changes in the animal body will be studied after the application of a complex herbal preparation.

Degree of implementation: no

List of published works within the framework of the project: (with indication of DOI, ISBN)

Кармалиев Р. С., Ертлеуова Б.О., Нуржанова Ф. Х., Сидихов Б. М. Оценка антимикробных свойств лекарственных растений для разработки комплексного растительного препарата // Ғылым және білім. 2024. № 1-1 (74) С. 28-40

DOI 10.52578/2305-9397-2024-1-1-28-40

Name of the project / program topic: AP23489173 "Development of a complex of veterinary and sanitary measures for bee diseases in the conditions of the West Kazakhstan region and technology for obtaining environmentally friendly bee products".

The name of the priority area of science development for which the application is submitted _6.Sustainable development of the agro-industrial complex.

The name of the specialized scientific research area: 6.1.Veterinary medicine

Scientific director of the project/program: Kaisar Kushaliev, doctor of veterinary sciences, professor.

The implementation period, its duration in months. 01.01.2024 - 31.12.2026 year, duration 36 month.         

The total amount of funding, and by year: 118311,409  thousand tenge,

2024 year – 33679,662 thousand tenge;

2025 year – 42310,353 thousand tenge;

2026 year – 42321,394 thousand tenge.

Objects of research, development or design: bee farms, bees, bee products

The purpose of the project / program: Monitoring of the epizootic situation of infectious and invasive bee diseases for the development of a complex of veterinary and sanitary and therapeutic and preventive measures for bee diseases and the introduction of scientifically based technologies to increase bee productivity to obtain environmentally friendly bee products.

Project / program objectives:

1. To monitor the veterinary and sanitary condition of beekeeping farms and epizootological monitoring in order to clarify the situation of infectious and invasive diseases.

2. Identify the factors causing various pathologies of bees in order to prevent their occurrence and spread.

3. Publication of 1 article in foreign or domestic publications recommended by the SHEQAС

Participation in 2 international conferences.

The results obtained and the novelty: (no more than 200 words)

 1. The veterinary and sanitary condition of beekeeping farms has been studied and assessed

1.1. Infectious and invasive diseases causing significant harm to bees and bee products have been identified_

2. The causes of bee diseases have been established, the sources and ways of introducing diseases, the degree of spread of infection (invasion) have been determined

3. Published:

1 article in domestic publications recommended by the SHEQAС

2 articles in international conferences.

The study of the epizootic situation and the spread of infectious and parasitic diseases of bees in the bee farms of the West Kazakhstan region, the patterns of spread and factors affecting the manifestation of particularly dangerous diseases, which will allow predicting the level of tension in the veterinary and sanitary situation, planning and developing therapeutic and preventive measures for the sustainable development of beekeeping.

Development of scientifically based technologies for keeping bees, which will increase the economic, technological, and social efficiency of the industry, increase the volume of production of bee products and expand opportunities for international cooperation in promoting bee products to the foreign market and the development of the beekeeping market as a whole.

Expected results:

1. The veterinary and sanitary condition of beekeeping farms will be studied and assessed.

1.1. Infectious and invasive diseases that cause significant harm to bees and bee products will be identified_

2. The causes of bee diseases will be established, the sources and ways of introducing diseases, the degree of spread of infection (invasion) will be determined

3. One article will be published in foreign or domestic publications recommended by the SHEQAС;

two articles in international conferences.

Degree of implementation: The results of the conducted research will be introduced into veterinary practice and used in carrying out therapeutic and preventive measures to combat bee diseases.

List of published works within the framework of the project: (with indication of DOI, ISBN)

1. Nurzhanova, F.H. Epizootological monitoring in bee farms of the West Kazakhstan region / Nurzhanova F.H., Satybaev B.G., Kairgalieva G.Z., Kushaliev K.Zh., Bayantasova S.M., Valitova N.V., Kozhaeva A., Agisheva E.R. // "Gylym zhane bilim", No. 3-1 (76) – 2024, pp. 163-173. DOI 10.52578/2305-9397-2024-3-1-163-173
2. Mendybaeva, E.R. Assessment of the quality and safety of various varieties of honey in the West Kazakhstan region / Mendybaeva E.R., Bayantasova S.M., Kairgalieva G.Z., Satybaev B.G., Kushaliev K.J. // Materials of the IX International scientific and practical conference "Modern achievements of biotechnology. Fundamental and applied aspects" and the conference "Innovative biotechnologies of natural and synthetic biologically active substances. Narochanye readings-16" (October 21-24, 2024). Stavropol, 2024, From 228-233. ISBN 978-5-6051787-8-1
3. International scientific and practical conference "World and Russian trends in beekeeping and apitherapy: realities and challenges of the future" November 14-16, 2024, FSBI "FNC Beekeeping" (Rybnoye).

Name of the program topic: BR23488151 «Development of effective methods of breeding waterfowl through selection and technological methods and information technologies»

The name of the priority area of science development for which the application is submitted: Sustainable development of the agro-industrial complex.

The name of the specialized scientific research area: Intensive animal husbandry.

Scientific director of the program: Nametov Askar- doctor of veterinary sciences, professor

The implementation period, its duration in months: 03.01.2024 – 12/31/2026 (36 months).

The total amount of funding, and by year: 288 922, 35 thousand tg.

2024 г – 90 738, 324 thousand tтg.

2025 г – 97 560, 182 thousand tg.

2026 г – 100 623, 844 thousand tg.

Objects of research, development or design: The research will be carried out on a collection herd of waterfowl from a poultry farm in the Northern region of Kazakhstan.

The purpose of the program: Development of effective ways of breeding waterfowl through selection and technological methods and information technologies.

Program objectives:

To achieve this goal, the following tasks must be solved:

1. Create a new breed of meat ducks.

2. To develop feeding rations for ducks of different age and gender groups.

3. To develop information technologies for automation of the production process in the cultivation of waterfowl.

Today, the task is urgent not only to preserve the numerous diversity of lines, breeds, populations, but also their rational use, both for the production of eggs and meat, and for the creation of new more highly productive breeds and crosses. 

Since the development of poultry farming will continue to be based on the use of hybrid poultry obtained as a result of crossing according to certain schemes, it is necessary to constantly work on increasing the heterosis effect based on the compatibility of breeds, crosses and lines.

The share of genotypic diversity in the total variability in most economically useful traits (egg production, precocity, live weight, etc.) is more fully manifested with proper cultivation and full-fledged feeding of poultry.

When growing and keeping linear and hybrid birds under the same conditions, it is possible to determine the relative value of a particular parent breed, line, cross in various crossing combinations and identify effective ways to use data to obtain a highly heterotic bird.

The efficiency of duck meat production largely depends on the payment of feed products, which is also considered an important task. It was believed that live weight selection was the simplest and most effective way to reduce feed costs, although the content of lean meat in the carcass may not increase.

Therefore, the choice of environmental conditions during the rearing of young animals plays an important role in improving the effectiveness of the assessment and selection of poultry for the reproduction of the herd. The "genotype—environment" interaction is defined in a two-factor dispersion complex as the proportion of the influence of a combination of genotypic and environmental factors.

In the structure of the cost of eggs and poultry meat, feed accounts for 60-70%. Reducing feed consumption per unit of production and increasing the efficiency of their assimilation can be achieved: firstly, by using high-quality feed products and proper preparation of feed for feeding; secondly, by using optimal feed recipes for the appropriate groups of poultry and, thirdly, by selecting appropriate feeding regimes and techniques.

Conducting economic analysis is an integral part of the work to optimize production activities and increase profits by improving production performance or by reducing costs.

Analyzing the production performance of a poultry farm is a difficult task. For its successful implementation, it is necessary to solve both the tasks of accounting for poultry stock and daily production indicators (poultry mortality, egg production, poultry slaughter, feed consumption and composition, transfer of poultry from the buildings of the repair young to the buildings of the parent herd, and others), and analysis of vaccination and prevention methods used at the poultry farm.

The purpose of automation, first of all, is to reduce the time spent by the building attendants and the dispatcher on calculating production indicators.

The technical level in the field of poultry farming in the Republic of Kazakhstan requires improvement.

The objectives of this project directly correspond to the strategic objectives of the Republic of Kazakhstan in the field of agriculture and food security. Improving the quality and efficiency of poultry production contributes to the development of the egg and meat industries and supports the country's strategic plans to provide food to the national market.

The results will meet the social demand for high-quality eggs and diurnal young, ensuring food safety and supporting the food industry. The economic and industrial interest in the results of the program is manifested in increasing the competitiveness of local producers and their ability to compete in the global market.

The results obtained and the novelty:

To increase the efficiency of poultry production, it is proposed to develop a digital small-sized machine in order to improve the quality and automatic sorting of incubation and commercial eggs. In addition, it is proposed to develop a sound stimulation device, the operation of which during the incubation of waterfowl eggs would ensure accelerated and synchronous withdrawal of daily young and would not only improve product quality, but also reduce human dependence and the likelihood of errors in the production process.

The task is an innovative solution that combines digital technologies with egg production, which makes it unique in the context of existing analogues. The fundamental difference lies in the development of a small-sized machine that not only determines quality indicators, but also automatically sorts eggs, which significantly increases the efficiency and accuracy of production processes.

Existing sorting and quality control methods remain largely manual and human-dependent. The task is a modern solution that will contribute to improving the technical level in this industry.

One of the reserves for increasing efficiency in poultry farming is considered to be the improvement of technological modes of egg incubation. In this direction, an important factor is to ensure accelerated and synchronous withdrawal of daily young in the incubator due to various stimulants, including sound ones.

Thus, automating the egg sorting and quality control processes will reduce the likelihood of human error, as well as ensure that eggs are sorted with high speed and accuracy. The use of a sound stimulation device during incubation will speed up the withdrawal of young animals from eggs.

Expected results:

Direct results.

There must be:

An application has been submitted for the breeding achievement of a new breed of meat ducks;

Recommendations on the preparation of feeding diets for ducks for different age and gender groups have been developed;

A mobile application has been developed for duck farms (at least 1.0 thousand heads), which allows calculating the cost of the raised poultry population;

A mobile application for the diagnosis of duck diseases has been developed;

An experimental sample of a small-sized digital machine for determining quality indicators and automatic sorting of incubation and commercial eggs has been made; 

A sound stimulation device has been developed to synchronize the output of daily young animals in the hatchery cabinets of the incubator;

Received 1 patent for a small-sized digital machine;

Young specialists will be involved, including 3 undergraduates, 2 doctoral students;

Published at least 2 (two) articles in peer-reviewed scientific publications indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 35 (thirty-five) and at least 6 (six) publications in foreign and domestic publications recommended by the By the Committee for Quality Assurance in Science and Higher Education of the Ministry of Science and Higher Education of the Republic of Kazakhstan for the publication of the main results of scientific activities. (Articles will be counted if they are published on the official website of the journal, including those with the status Article in Press or Early Access.)

As part of the implementation of scientific research under the program, at least 2 (two) scientific publications will be published for the entire period of research in peer-reviewed scientific publications included in the quartiles (Q1, Q2, Q3) of the Web of Science database or having a Cite Score percentile in the Scopus database of at least 30 (thirty).

The end result:

The expected social and economic effect.

The proposed program is in line with the country's strategic development policy and will make a significant contribution to the poultry industry. 

The implementation of the obtained results in the poultry industry will increase the profitability of poultry production by increasing labor productivity, provide new jobs, which will have a social and economic effect.

The expected environmental effect.

This program will not have a negative impact on the environment, will not entail additional adverse factors, since, during its implementation, veterinary and sanitary, zootechnical requirements for the cultivation and maintenance of waterfowl will be observed, and the excreted manure saturated with trace elements and nutrients will be used as a soil fertilizer for growing crops.

Degree of implementation:

After the completion of the project, a mobile application for duck farms (at least 1.0 thousand heads) will be developed, allowing to calculate the cost of poultry livestock; a mobile application for the diagnosis of duck diseases; an experimental sample of a digital small-sized machine for determining quality indicators and automatic sorting of incubation and commercial eggs; a sound stimulation device for synchronizing the output of daily young animals in the hatchery cabinets of the incubator.

Due to these developments in poultry farming, novice entrepreneurs of the poultry industry can avoid many mistakes in poultry breeding, financial losses, and competently plan the need for necessary consumables, thereby increasing the volume of poultry meat production.

List of published works within the framework of the program:

Name of the project / program topic: BR24993125 «Rational technology of using cullet in the production of silicate bricks to increase the thermal protection of enclosing structures during the modernization of housing and communal services facilities»

The name of the priority area of science development for which the application is submitted 2) Energy, advanced materials and transport

The name of the specialized scientific research area: 9. Surface engineering and materials processing technologies.

Scientific director of the project/program: Montaev Sarsenbek - doctor of technical sciences, professor

The implementation period, its duration in months. 01.07.2024-31.12. 2026 year, duration 30 month.         

The total amount of funding, and by year: 118 251, 100 thousand tenge,

2024 year – 29 785, 700 thousand tenge;

2025 year – 44 196, 200 thousand tenge;

2026 year – 44 269 200 thousand tenge.

Objects of research, development or design:

Based on the general technical and economic advantages, develop a technology for the complex processing of broken glass with the aim of using it as a resource-saving and modifying additive in the production of sand-lime bricks. Develop rational technological parameters for the production of sand-lime bricks taking into account the use of processed finely dispersed broken glass powder. Select the necessary technological equipment for processing broken glass, providing a powdered silicate mass ready for subsequent technological operations.

The purpose of the project / program:

Development of technology for complex processing of broken glass and rational technological parameters for the production of sand-lime bricks in the composition of quartz sand and a silicate mixture.

Development of optimal compositions of silicate masses with additives of finely dispersed broken glass powder that meet the requirements for resource conservation, energy efficiency, ecology and operational qualities of finished products;

Justification of the technical and economic efficiency of the developed technology and development of recommendations for the purpose of implementing and commercializing the technology.

Project / program objectives:

Sampling of window and container glass waste at enterprises engaged in the production of double-glazed windows and landfills for the processing of municipal solid waste (MSW) in Western Kazakhstan.

Analysis and real assessment of the resulting unsorted glass waste by type, by fractions, the presence of impurities in order to create initial data for further research on their processing.

Research of the physical and mechanical properties and chemical compositions of the resulting unsorted glass waste.

Development of technological parameters for crushing and grinding and determination of the most optimal granulometric composition of glass powder based on unsorted glass waste.

Development of optimal compositions of silicate masses with the addition of crushed glass powder to obtain sand-lime bricks according to the criteria of energy efficiency and resource conservation.

Establishment of the main patterns of change in the physical and mechanical properties and structure formation processes depending on the content of glass powder and the technological conditions of autoclaving;

Development of rational technological parameters for obtaining sand-lime bricks with the addition of glass powder at the stage of raw material preparation, dosing, mixing, molding and autoclaving;

Development of a rational technological scheme for the production of sand-lime bricks based on the processing of broken glass into a composition with a silicate mixture including quartz sand from the West Kazakhstan deposit;

Release of a pilot batch of sand-lime bricks in the conditions of the sand-lime brick production plant of West Kazakhstan Corporation of Building Materials JSC

Conducting scientific and experimental work and testing to determine their physical and mechanical properties and filing an application for a patent for the technology being developed.

The results obtained and the novelty: -

Expected results:

A literature review and patent search will be conducted in the area of ​​research.

Work will be carried out to select samples of window and container glass waste at enterprises engaged in the production of double-glazed windows and landfills for the processing of municipal solid waste (MSW) in Western Kazakhstan.

An analysis and real assessment of the resulting unsorted glass waste by type, by fractions, the presence of impurities will be carried out in order to create initial data for further research on their processing.

The physical and mechanical properties and chemical compositions of the resulting unsorted glass waste will be studied.

The technological parameters of crushing and grinding will be developed and the most optimal granulometric compositions of glass powder based on unsorted glass waste will be determined.

Optimal compositions of silicate masses with the addition of glass powder will be developed to obtain sand-lime bricks according to the criteria of energy efficiency and resource conservation. The main patterns of changes in physical and mechanical properties and structure formation processes depending on the content of glass powder and the technological conditions of molding and autoclaving will be established.

Rational technological parameters for obtaining sand-lime bricks with the addition of glass powder at the stage of raw material preparation, dosing, mixing, molding and autoclaving will be developed.

The necessary technological equipment for processing cullet will be selected, providing a powdered silicate mass ready for subsequent technological operations.

A rational technological scheme for the production of sand-lime bricks will be developed based on the processing of cullet into a composition of a silicate mixture including quartz sand from the West Kazakhstan deposit.

Pilot-industrial tests of the developed silicate mixture compositions will be carried out and a pilot batch of sand-lime bricks will be produced in the conditions of the sand-lime brick production plant of West Kazakhstan Corporation of Building Materials JSC.

An application will be filed to obtain a patent for the technology being developed. An analysis of the technical and economic efficiency of sand-lime brick production using glass powder based on the processing of unsorted cullet will be conducted.

Recommendations will be developed for the purpose of implementing and commercializing the technology.

Scientific and experimental work will be carried out to test pilot batches of sand-lime bricks.

Based on the general technical and economic advantages, a technology for the comprehensive processing of cullet will be developed in order to use it as a resource-saving and modifying additive in the production of sand-lime bricks.

Rational technological parameters for the production of sand-lime bricks will be developed taking into account the use of processed fine cullet powder.

Based on the results of the implementation of the scientific and technical products program, new technologies, methods, technical documentation, recommendations for solving problems, an act of implementation for pilot developments, new materials, recommendations for implementation will be prepared.

The following will be published:

- at least 5 (five) articles in journals recommended by the KOKNVO;

- at least 4 (four) articles and (or) reviews in peer-reviewed scientific publications in the scientific area of ​​the program, included in the 1st (first), 2nd (second) and (or) 3rd (third) quartile by impact factor in the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 50 (fifty);

- at least 1 (one) monograph or textbook in a foreign and (or) Kazakhstani publishing house, recommended by the academic council and (or) scientific and technical council of the applicant's organization;

- at least 1 (one) intellectual property object (patent; for

applications in the field of information technology - author's certificate), registered with the National Institute of Intellectual Property of the Republic of Kazakhstan.

Degree of implementation:

Work on the project began in 2024 and is at the initial stage of implementation.

List of published works within the framework of the project: -

Name of the project / program topic: AP19577616 «Study of breed-specific traits in domestic horse breeds by resequencing and transcriptomic analysis»

The name of the priority area of science development for which the application is submitted 6. Life and Health Science

The name of the specialized scientific research area: 6.2 Innovative biological research to increase the productivity and sustainability of plant varieties and animal breeds in agriculture

Scientific director of the project/program: Beishova Indira - doctor of biological sciences, associate professor

The implementation period, its duration in months. 1.02.2023-31.12.2025 y.y., 35 months

The total amount of funding, and by year: 75 000, 00 thousand tenge,

2023 year – 25 000,00 thousand tenge;

2024 year – 25 000,00 thousand tenge;

2025 year – 25 000,00 thousand tenge.

Objects of research, development or design: Domestic horse breeds (mugalzhar, kushum, Kazakh breed: Jabe, Naiman and Adai types)

The purpose of the project / program: To reresequence the complete genome of domestic horse breeds (Mugalzhar, Kushum, Kazakh breed: Jabe, Naiman and Adai types), to identify specific genetic variants under selections pressure, to search for breed-specific sections of genome to increase the genetic potential, early prediction of their breeding value, conservation and improvement of genetic resources.

Project / program objectives:

1. To form a sample of the studied groups of domestic horse breeds

2. To carry out the whole genome resequencing and its bioinformatic analysis

3. To compare the distribution of heterozygosity in the genomes of domestic horse breeds with other breeds

4. To determine single nucleotide polymorphisms (SNP), insertions/deletions (INDEL), copy number variations (CNV), structural variations (SV) in the genome of the studied groups of domestic horse breeds

5. To establish possible functional variants of the genome sequence responsible for a certain phenotype

6. To identify unique or specific genetic variants and create a database of genomic variations of domestic horse breeds

7. Identification of unique miRNA transcription profiles in different domestic horse breeds

8. To develop recommendations for assessing the genetic potential of domestic horse breeds, early prediction of their breeding value, conservation and improvement of genetic resources

The results obtained and the novelty: (no more than 200 words)

The complete genome of domestic horse breeds has been resequenced and its bioinformatic analysis has been carried out.The distribution of heterozygosity in the genomes of domestic horse breeds was compared with other breeds.Single nucleotide polymorphisms (SNP), insertions/deletions (INDEL), copy number variations (CNV), and structural variations (SV) in the genome of the studied groups of domestic horse breeds were determined.Possible functional variants of the genome sequence responsible for a certain phenotype have been established. It was revealed that the distribution of heterozygosity in domestic breeds is more variable between different parts of the genome, while in foreign breeds heterozygosity is more evenly distributed. SNP, INDEL, CNV and SV have been found, which may be associated with differences in the phenotypic characteristics and health of horses. The analysis of genetic variants in the genomes of domestic horse breeds revealed a significant number of mutations, both known and new. These variants influence a variety of biological processes, including growth, development, immune response, and metabolism. The detected SNP, INDEL and structural variations can be used to improve breeding programs and increase animal resistance to diseases.

Expected results:

As a result of the project implementation, there will be:

- a sample of the studied groups of domestic horse breeds was formed

- the complete genome was resequenced and its bioinformatic analysis was carried out

- the distribution of heterozygosity in the genomes of domestic horse breeds was compared with other breeds

- single nucleotide polymorphisms (SNP), insertions/deletions (INDEL), copy number variations (CNV), structural variations (SV) in the genome of the studied groups of domestic horse breeds were determined

- possible functional variants of the genome sequence responsible for a certain phenotype have been established

- unique or specific genetic variants have been identified and a database of genomic variations of domestic horse breeds has been created

- unique miRNA transcription profiles have been identified in different domestic horse breeds

- a recommendation has been developed to assess the genetic potential of domestic horse breeds, early prediction of their breeding value, conservation and improvement of genetic resources.

Degree of implementation: These studies will allow us to create promising developments for planning breeding work, programs for breeding domestic horse breeds.

List of published works within the framework of the project: (with indication of DOI, ISBN)

1.Beishova I. S., Shamshidin A. S., Kuzhebayeva U. zh., Ulyanov V. A., Ulyanova T. V., Bekova G. S., Salimova D. K. The formation of the issue and the release of domestic resources for the conduct of full-fledged restitution / scientific and practical Journal zkatu named after Zhangir Khan "Science and education". - 2024. - №3-2 (76). - P.140-149. DOI 10.52578/2305-9397-2024-3-2-140-149

Name of the project / program topic: AP23488282«Development of a system for intravital evaluation and prediction of meat quality of Aberdeen Angus cattle raised in Kazakhstan».

The name of the priority area of science development for which the application is submitted 6. Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: 6.5 Intensive animal husbandry

Scientific director of the project/program: Ulyanova Tatiana -  PhD,

The implementation period, its duration in months. 01.01.2024 - 31.12.2026 year, duration 36 month.         

The total amount of funding, and by year: 120 000,0 thousand tenge,

2024 year – 34 000,0 thousand tenge;

2025 year – 43 000,0 thousand tenge;

2026 year – 43 000,0 thousand tenge.

Objects of research, development or design:_ cattle of the Aberdeen Angus breed

The purpose of the project / program: To develop approaches to genetic testing and identify genetic markers for meat productivity and beef quality for use in breeding of Aberdeen Angus cattle bred in Kazakhstan using DNA markers associated with food raw material quality.

Project / program objectives:

1. Establish a sample of Aberdeen Angus cattle and select biological material.

2. Test existing and developing methods for sample preparation and nucleic acid extraction.

3. To test the AS-PCR method for genotyping Aberdeen Angus cattle for the leptin gene (LEP) in the context of assessing meat productivity and quality of food raw materials.

4. To test the PCR-RFLP method for genotyping the thyroglobulin gene (TG5) in Aberdeen Angus cattle in relation to the evaluation of meat productivity and quality of food raw materials.

5. To test the real-time PCR, PCR-RFLP methods with allele-specific primers for genotyping Aberdeen Angus cattle for the diacylglycerol O-acyltransferase 1 gene (DGAT1) in the context of assessing meat productivity and quality of food raw materials.

6. Genotyping of Aberdeen Angus cattle bred in Kazakhstan for lipid metabolism genes.

7. To develop a PCR-SBT (nucleic acid sequencing typing) method for genotyping Aberdeen Angus cattle for the LEP, TG5 and DGAT1 genes in the context of assessing meat productivity and quality of food raw materials.

8. To characterise the genetic structure of the studied animals based on the genes for leptin, thyroglobulin and diacylglycerol O-acyltransferase 1.

9. To carry out a comparative analysis of the distribution of allelic variants and different genotypes of the LEP, TG5 and DGAT1 genes in different breeds and groups.

10. To evaluate the influence of single and complex genotypes for the leptin, thyroglobulin and diacylglycerol O-acyltransferase 1 genes on meat productivity and raw material quality and to identify genetic markers for use in breeding.

The results obtained and the novelty: (no more than 200 words) _______________________________________________________________________________________________________________________________________________________________________________________________________________________________________

Expected results:

- a sample of Aberdeen Angus cattle was formed and biological material was selected;

- the existing and developed methods of sample preparation and extraction of nucleic acids have been tested;

- the AS-PCR method has been tested for genotyping Aberdeen Angus cattle by leptin (LEP) gene, in the context of assessing meat productivity and the quality of food raw materials;

- the PCR- RFLP method for genotyping Aberdeen Angus cattle by the thyroglobulin (TG5) gene has been tested in the context of assessing meat productivity and the quality of food raw materials;

- methods of Real-Time PCR, PCR- RFLP with allele-specific primers for genotyping Aberdeen Angus cattle by the diacylglycerol O-acyltransferase 1 (DGAT1) gene have been tested in the context of assessing meat productivity and the quality of food raw materials;

- genotypes of cattle of the Aberdeen Angus breed bred in Kazakhstan for lipid metabolism genes have been established;

- a PCR-SBT method (nucleic acid sequencing typing) has been developed for genotyping Aberdeen Angus cattle by the LEP, TG5 and DGAT1 genes in the context of assessing meat productivity and the quality of food raw materials;

- the genetic structure of the studied animals was characterized by the genes for leptin, thyroglobulin and diacylglycerol O-acyltransferase 1;

- a comparative analysis of the distribution of allelic variants and different genotypes of the LEP, TG5 and DGAT1 genes in different breeds and groups was carried out;

- the influence of single and complex genotypes on the genes for the leptin, thyroglobulin and diacylglycerol O-acyltransferase 1 on meat productivity and quality of raw materials was evaluated, and genetic markers for use in breeding were identified.

Degree of implementation: These studies will allow cattle breeders to breed Aberdeen Angus cattle based on the identified animals with high genetic potential of productivity and quality of products obtained from them through the use of marker-associated selection, as well as the results of the project will help determine the current state of the Aberdeen Angus breed for the development of future programs to increase its number.

List of published works within the framework of the project: (with indication of DOI, ISBN)

Name of the project / program topic: АР2349274 «Development of technologies for improving the ecological and meliorative state of estuaries and increasing their productivity».

The name of the priority area of ​​science development for which the application is being submitted: 6. Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: 6. Intensive farming and crop prodactuon

Scientific director of the project/program: Nagiyeva Aliya, PhD.

The implementation period, its duration in months: 01.01.2024 – 12.31.2026, duration 36 months.

Total amount of financing, and by year: 103,629,903 tg,

2024 – 33,916,730.0 tenge;

2025 – 34,785,227.0 tenge;

2026 – 34,927,946.0 tenge.

Objects of research, development or design: estuaries

The aim of the project / program is to develop technologies for improving the ecological and meliorative state and increasing the productivity of estuaries

Project/program objectives:

1. Assessment of the ecological-hydrogeological-meliorative state of estuaries based on studies of soil indicators, the composition of the dominant taxa of microbiomes, hydrogeological and hydrochemical characteristics of groundwater, the regime and frequency of flooding, the qualitative composition of herbage.

2. Study of the influence of techniques for maintaining the water-salt regime of the soil and increasing the productivity of natural herbage on the ecological-hydrogeological-meliorative state of estuaries.

3. Substantiation of the influence of the landscape-ecological approach to the reclamation of estuarine lands on the maintenance of an optimal ecological-reclamation situation and restoration of the productivity of the natural herbage of degraded areas of the estuary.

The results obtained and the novelty:

More than 70% of engineering estuaries are flooded with violation of technological regimes.

Due to long-term flooding in the conditions of natural relief, an uneven impact on the landscape of the area occurs, which leads to a change in the water-salt balance of the territory, degradation of valuable plant species, and a decrease in the productivity of the natural herbage of estuaries.

Such a model of the development of secondary salinization processes was not considered during the design period and criteria for the intensity of the impact of estuarine irrigation on the formed estuarine agricultural landscape were not developed for these soil reclamation conditions.

These studies will be aimed at developing technologies to improve the ecological and meliorative state and increase the productivity of estuaries.

Currently, the use of modern methods of high-performance sequencing with the combination of traditional methods of soil science will allow a more informative study of the distribution of soil microorganisms to justify solutions to improve the ecological and reclamation state of agricultural landscapes.

The substantiation of the landscape-ecological approach to the reclamation of estuarine lands on the ecological-hydrogeological-meliorative state of estuaries, based on the established norms of the natural object, standardized parameters of the territory, the interval of their natural fluctuations, is a new level in scientific research, has significant scientific and technical potential.

The study of the microbial community on estuarine landscapes in conditions of long-term flooding, the change of which is an important symptom of violations of the natural processes of maintaining soil fertility, will have a significant impact on the level of research and scientific and technical potential. 

The use of modern methods of high-performance sequencing with the combination of traditional methods of soil science in assessing the ecological and reclamation state of estuarine landscapes is a new and promising area of research.

Expected results:

Boudout:

- the influence of the flooding regime and chemical reclamation of estuary soils on the formation of the water-salt regime of the soil, as well as on the productivity of natural herbage, has been studied;

- а technology has been developed to improve the ecological and reclamation condition of estuaries and increase their productivity;

- 2 (two) articles and (or) reviews have been published in peer-reviewed scientific publications indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 50 (fifty);

- 1 (one) article has been published in a peer-reviewed foreign or domestic publication recommended by the CQASHE;

- recommendations have been developed to restore productivity and improve the reclamation condition of engineering estuaries.

Degree of implementation: Recommendations will be developed for the implementation of research results

List of published works within the framework of the project:

Publications are scheduled for 2025 and 2026

Name of the project / program topic: АР23486846 «Economic Assessment of the Impact of Wild Animal Populations (Saigas) on Agriculture and Strategies for Reducing Damage».

The name of the priority area of science development for which the application is submitted 6) Sustainable development of the agro-industrial complex__________

The name of the specialized scientific research area: 9. Sustainable development of rural areas and the economy of the agro-industrial complex __

Scientific director of the project/program: Aigul Kazambayeva – candidate of economic sciences, associate professor in the specialty «Economics».

The implementation period, its duration in months. 09.09.2024 - 31.12.2026 year, duration 28 month.         

The total amount of funding, and by year: 90 000 thousand tenge,

2024 year – 30 000 thousand tenge;

2025 year – 30 000 thousand tenge;

2026 year – 30 000 thousand tenge.

Objects of research, development or design: Assessing the economic impact of wildlife populations, particularly saigas, on the agricultural sector in Kazakhstan.

The purpose of the project / program: is to conduct an economic assessment of the impact of wild animal populations (saiga) on agriculture and develop organizational and economic measures to reduce damage.

Project / program objectives:

1. Analysis of the number and populations of saigas, as well as measures for their regulation at the present stage.

2. A comprehensive analysis of the current situation, problems and losses, as well as an assessment of the costs of restoring agricultural production from the negative impact of saiga populations in the regions.

3. To develop a methodology for determining the loss of productivity of agricultural land due to the loss of saiga and the principles of subsidizing costs.

4. To offer economically sound recommendations for farmers and agricultural enterprises to manage the risks associated with the spread of saiga populations.

5. Develop a system for managing saiga populations and ways to minimize risks and losses for agricultural producers, as well as maximize the use of resources obtained as a result of regulating their numbers.

6. Development of mathematical models for forecasting the dynamics of saiga populations in the West Kazakhstan region and assessment of their impact on agricultural production.

The results obtained and the novelty: (no more than 200 words) _______________________________________________________________________________________________________________________________________________________________________________________________________________________________________

Expected results:

1. A comprehensive analysis of the size and distribution of saiga populations will be carried out, and the effectiveness of existing measures to regulate them will be evaluated.

2. A comprehensive analysis of the economic losses and costs associated with the restoration of agricultural production in different regions caused by the negative impact of saiga populations will be carried out.

3. A methodology will be developed to assess the loss of agricultural productivity caused by saigas. This will provide an accurate quantification of the impact of these animals on crop yields and agricultural efficiency. In addition, it is planned to develop subsidy principles to compensate farmers for these losses, which will help to mitigate the financial impact on the agricultural sector.

4. Economically sound recommendations will be developed for farmers and agricultural enterprises to manage the risks associated with the spread of saiga populations. These recommendations will aim to reduce damage and increase the resilience of the agricultural sector, ensuring more efficient and informed resource management.

5. Mathematical models will be developed specifically to predict changes in saiga populations in West Kazakhstan Oblast. These models will also assess the impact of these changes on agricultural production in the region.

6. A comprehensive saiga population management system will be established, which includes measures to minimize the risks and losses experienced by agricultural producers due to the actions of these animals.

Based on the results of the conducted research, there will be published:

- at least 2 (two) articles and (or) reviews in peer-reviewed scientific publications indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 50 (fifty);

- as well as at least 1 (one) article or review in a peer-reviewed foreign or domestic publication recommended by the KOKNVO;

- or at least 1 (one) article or review in a peer-reviewed scientific publication indexed in the Science Citation Index Expanded and included in the 1st (first) or 2nd (second) quartile by impact factor in the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 65 (sixty five);

- as well as at least 1 (one) article or review in a peer-reviewed foreign or domestic publication recommended by the KOKNVO.

Degree of implementation: ________________________________________________

List of published works within the framework of the project: (with indication of DOI, ISBN)

… _____________________________________________________________________

Name of the project / program topic: AP22782840 «Search and analysis for genomic markers associated with productive qualities in Mugaljar horses using SNP-genotyping»

The name of the priority area of science development for which the application is submitted: Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: Bioinformatics and digitalization in the agro-industrial complex system

Scientific director of the project/program: Kovalchuk Alexandr, PhD

The implementation period, its duration in months. 01.06.2024-31.12.2026 y.y., 31 months

The total amount of funding, and by year: 89,961.9 thousand tenge,

2024 year – 29,986.9 thousand tenge;

2025 year – 29,994.7 thousand tenge;

2026 year – 29,980.3 thousand tenge.

Objects of research, development or design: Mugaljar horses

The purpose of the project / program: the aim of the project is to identify genomic markers associated with productive traits in mugaljar horses using snp genotyping technology

Project / program objectives:

1 To study genetic diversity of horses of the Mugaljar breed in different regions of Kazakhstan using high-density genotyping:

1.1 Determine the degree of genetic diversity within the breed

2. Identify polymorphisms in the genome regions associated with economically important traits in the Mugaljar horses:

2.1 Identify associations between specific SNPs and productive traits in Mugaljar horses

2.2 Identify genome regions containing SNP markers associated with productive traits

2.3 Perform functional analysis of genes and biological processes associated with the identified genomic markers

3 Identify and propose for use genetic markers associated with the productive qualities of horses of the Mugaljar breed

3.1 Select oligonucleotide sequences containing genetic markers associated with productive qualities of Mugaljar horses

3.2 Make recommendations on the use of genetic markers for selection and improvement of horses of Mugaljar breed

The results obtained and the novelty: (no more than 200 words) The research project aims to identify genomic markers associated with productive qualities in the Mugaljar horse breed using SNP genotyping technology. The Mugaljar horse breed, known for its resistance to harsh steppe conditions, is a subject of interest because of its outstanding productive characteristics.

The project involves interdisciplinary research, combining knowledge from the fields of genetics, animal science and bioinformatics. Using high-density genotyping, the project aims to investigate the genetic diversity of the breed, identify polymorphisms in genome regions associated with economically important traits, and identify genomic markers associated with productive traits.

The work involves analyzing associations between SNPs and productive traits, as well as functional analysis of genes and biological processes associated with the identified genetic markers. At the end of the project, genetic markers will be proposed for use in the selection and improvement of Mugaljar breed horses.

Expected results:

1. The study of genetic diversity of horses of the Mugalzhar breed in different regions of Kazakhstan will be carried out using high-density genotyping;

2. Polymorphisms associated with economically important traits in horses of the Mugaljar breed will be identified;

3. Genetic markers associated with productive qualities of horses of Mugaljar breed will be determined and proposed for use.

Degree of implementation:

List of published works within the framework of the project: (with indication of DOI, ISBN)

Name of the project topic: AP19579335 «Technological justification for the intensification of waterfowl meat production in the West Kazakhstan region».

The name of the priority area of science development for which the application is submitted: «Sustainable development of the agro-industrial complex and safety of agricultural products».

The name of the specialized scientific research area: 5.1. «Development of intensive animal husbandry».

Scientific director of the project: «Sustainable development of the agro-industrial complex and safety of agricultural products».

The implementation period, its duration in months. 01.02.2023 – 31.12.2025 (35 months).

The total amount of funding, and by year: 73830046,01 tg,

2023 г. – 24 378 896,39 tg;

2024 г. – 24 767 150,96 tg;

2025 г. – 24 683 998,66 tg.

Objects of research, development or design: The initial material for the work will be geese of the Linda breed and ducks of the Medeo breed.

The purpose of the project: The aim of the project is to develop technological methods to intensify the production of waterfowl meat in the West Kazakhstan region.

Project objectives:

To achieve this, scientific and experimental research will be conducted by solving the following and interrelated tasks that require consistent implementation:

According to the intensification of the technology for growing young geese of the Linda breed for meat:

- to form experimental groups of goslings of the Linda breed and make balanced diets with the addition of biologically active additives;

- study the chemical composition of feed;

- develop formulas for feed mixtures for goslings of various age and sex groups;

- to determine the most optimal methods for intensifying the technology of growing geese;

- to study the growth and development, safety, productive performance of experimental goslings;

- to study the digestibility of nutrients in diets in the body of experimental goslings;

- to study the hematological parameters of experimental goslings;

- to study the meat productivity of experimental goslings;

- conduct an organoleptic assessment and study the morphological, chemical composition of goose meat;

- to calculate the economic efficiency of the intensification of geese breeding in the conditions of the West Kazakhstan region.

According to the intensification of the technology of growing young ducks of the Medeo breed for meat:

- to form experimental groups of ducklings of the Medeo breed and make balanced diets with the addition of biologically active additives;

- study the chemical composition of feed;

- develop formulas for feed mixtures for ducklings of various age and sex groups;

- to determine the most optimal methods for intensifying the technology of growing ducks;

- to study the growth and development, safety, productive performance of experimental ducklings;

- to study the digestibility of nutrients in diets in the body of experimental ducklings;

- to study the hematological parameters of experimental ducklings;

- to study the meat productivity of experimental ducklings;

- conduct an organoleptic assessment and study the morphological, chemical composition of duck meat;

- to calculate the economic efficiency of intensifying the cultivation of ducks in the conditions of the West Kazakhstan region.

The results obtained and the novelty:

For the first time in the conditions of the Western region of Kazakhstan, an effective technology for intensifying the production of waterfowl meat will be developed, research will be conducted to study the productive, biological and physiological qualities, hematological parameters of geese of the Linda breed and ducks of the Medeo breed. Also, formulations of feed mixtures will be developed and balanced feeding rations will be compiled.

The practical significance of the project lies in the fact that the conducted research will allow us to develop technological methods for intensifying meat production for high efficiency of meat production of poultry meat products, and significantly increase the profitability and competitiveness of the industry in Kazakhstan.

Research results:

The conditions of feeding and keeping of waterfowl in the West Kazakhstan region have been studied.

To complete the tasks, control (I, n =50/50) and experimental (II, n=50/50; III, n=50/50) groups of 100 heads each were formed. The birds were selected by the method of a group of analogues in terms of live weight and overall development. The live weight of daily ducklings ranged from 47.6 to 52.4 g. Differences in the live weight of ducklings of all groups at the age of 7 days were insignificant, and averaged 216.7 g. 

Samples of the main types of concentrated feeds (soy, barley, wheat, rye, peas, wheat bran) were selected, and the nutritional value of grain feeds was analyzed. The research results showed that in grain feeds, namely soy, barley, wheat, rye, peas, the content of metabolic energy ranged from 9.8 to 13.2 MJ, and respectively amounted to 13.2; 11.0; 10.2; 9.8 and 10.5 MJ.

According to the results of the chemical composition of the feed, balanced formulations of feed mixtures for feeding experimental groups of ducks were compiled. Feeding of experimental groups of birds in all groups was carried out in two–phase periods: 1-14 and 15-49 days.

The content of crude protein in the diet of young animals of the III experimental group was comparatively higher than the peers of the I control and II experimental groups by 7.3 and 15.2%, respectively. In subsequent periods of growth (from the age of 15 days), Protein-vitamin-mineral concentrate (PVMC), a protein-feed mixture in different dosages, and a mineral composition additive were added to the diet.

As a result of production experiments, the data obtained on the dynamics of live weight in the studied groups of young ducks indicate that the addition of various feed additives to the diet has a positive effect on the productive indicators of birds.

Expected results:

Experimental groups of goslings of the Linda breed and ducks of the Medeo breed will be formed;

Balanced diets with the addition of biologically active additives will be compiled; 

The chemical composition of the feed will be studied;

Formulations of feed mixtures for waterfowl of various sex and age groups will be developed;

The most optimal methods of intensification of geese cultivation technology will be determined;

The growth and development, safety, and productive indicators of experimental birds will be studied;

The digestibility of dietary nutrients in the body of experimental goslings and ducklings will be studied;

Hematological parameters of experimental goslings and ducklings will be studied;

The meat productivity of experimental goslings and ducklings will be studied;

An organoleptic assessment will be carried out and the morphological and chemical composition of the meat will be studied;

The economic efficiency of the intensification of the cultivation of geese and ducklings in the conditions of the West Kazakhstan region will be calculated.

According to the results of the project, at least 2 (two) will be published for the entire period of implementation articles and (or) reviews in peer-reviewed scientific publications in the scientific field of the project, indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 35 (thirty-five) and at least 1 (one) article or review in a peer-reviewed foreign or domestic publication, recommended by the Committee for Quality Assurance in Science and Higher Education of the Ministry of Science and Higher Education of the Republic of Kazakhstan for the publication of the main results of scientific activities.

It is planned to publish 1 (one) monograph. The monograph will present an original scientific work and is based on the generalization of the results of its own research within the framework of the project.

As part of the Project, the following scientific, technical, and design documentation will be received:

- 1 (one) methodological recommendation will be developed.

Based on the results of the study, it will be implemented into production and will be confirmed by 1 (one) Implementation Act indicating the achieved economic effect and recommendations for implementation.

Degree of implementation:

The results of the research will be distributed among direct potential consumers, the community of scientists and the general public, by making presentations at international conferences, publishing articles, and publishing recommendations.

The implementation of the Project will contribute to an increase in the production of poultry meat products (goose and duck meat), an increase in poultry meat consumption per capita, the creation of additional jobs, and an increase in the competence of specialists and staff in agricultural enterprises of various forms of ownership. The results of scientific research will increase the production of poultry meat products, which will have a social effect

List of published works within the framework of the project:

 1. Nugmanova A. E. history and prospects of development of UTKOVODSTVO in the West Kazakhstan region / Nugmanova A. E., Makhimova zh. N., Sengaliyev E. M., Batyrgaliyev E. A. / «Education and science" scientific journal of the agricultural and Technical University named after Zhangir Khan, 2023. №3-2 (72),2 -Department-S. -322. https://ojs.wkau.kz/index.php/gbj/issue/view/72/85 / DOI 10.52578/2305-9397-2023-3-2-322-333

Name of the project / program topic: AP23487950 «Study of genomic associations and productive traits in the Adai type of Kazakh horse»

The name of the priority area of science development for which the application is submitted: Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: Bioinformatics and digitalization in the agro-industrial complex system

Scientific director of the project/program: Kovalchuk Alexandr, PhD

The implementation period, its duration in months. 02.08.2024-31.12.2026 yy., 29 months

The total amount of funding, and by year: 119,805.3 thousand tenge,

2024 year – 33,848.7 thousand tenge;

2025 year – 42,965.4 thousand tenge;

2026 year – 42,991.2 thousand tenge.

Objects of research, development or design: Adai type of Kazakh horse

The purpose of the project / program: the aim of the project is to study the associations between genotypes and productive traits in the kazakh horse of the adai type in order to optimize breeding programs and improve productive traits

Project / program objectives:

1. Collect and annotate phenotypic data, including animal productive traits

2. Implementation of genotyping of representatives of the Kazakh horse of the Adai type

2.1 Identification of gene variants and genetic markers associated with productive traits in representatives of the Kazakh horse of the Adai type.

3. Analyze genotypic and phenotypic data to identify statistically significant associations.

3.1 Perform bioinformatic analysis of detected genetic variants

4. Provide recommendations for breeders aimed at improving the productive traits of the Kazakh horse of the Adai type.

The results obtained and the novelty: (no more than 200 words) The idea of the scientific project is to identify genomic markers associated with productive traits of the Kazakh horse of the Adai type using SNP genotyping technology. The Adai type of Kazakh horse differs from others in its adaptability to harsh steppe conditions and adaptation to life in a herd, and is also of interest for its productive traits.

The project covers a wide range of research, combining knowledge from genetics, animal science and bioinformatics.

Expected results:

1. A study of the genetic diversity of the Kazakh horse of the Adai type will be conducted in different regions of Kazakhstan using high-density genotyping;

2. To identify polymorphisms associated with economically significant traits in the Kazakh horse of the Adai type;

3. Genetic markers associated with the productive traits of the Kazakh horse of the Adai type will be identified and proposed for use.

Degree of implementation:

List of published works within the framework of the project: (with indication of DOI, ISBN)

Name of the project / program topic: АР23487758 « Development of a zero-tillage seeder with an automated system for strip sowing of various crops with simultaneous application of mineral fertilizers ».

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex.

The name of the specialized scientific research area: Technical support and modernization of agro-industrial complex.

Scientific director of the project/program: Kubasheva Zhanna, Candidate of technical sciences, associate professor

The implementation period, its duration in months. 01.01.2024 - 30.12.2026 year, duration 36 month.         

The total amount of funding, and by year: 120 000, 000 thousand tenge,

2024 year – 34 000, 000 thousand tenge;

2025 year – 43 000, 000 thousand tenge;

2026 year – 43 000 000 thousand tenge.

Objects of research, development or design: The technological process of sowing seeds of various crops with simultaneous application of mineral fertilizers.

The purpose of the project / program: Increasing the yield of various crops and reducing competition between seeds for nutrients by developing a working body of a seeder for zero farming with an automated dosing device system for sowing seeds of various crops with simultaneous application of mineral fertilizers.

Project / program objectives:

1. Create a wavy seedbed by improving the working body of the seeder and substantiating its optimal parameters so that the seeds after leaving the seed duct are located in the wavy seedbed and do not move further.

2. To justify the parameters of the ripper of the disc coulter to improve the ability to go deeper to the desired depth while minimizing traction resistance.

3. To develop a parallel mechanism for the working body so that the disc coulter with a ripper is deepened to a depth of 70 mm.

4. Develop a group of seed ducts for feeding seeds from a dosing device to a wavy seedbed.

5. To develop a six-row seeder for conducting field experiments.

6. To develop an automated system for a six-row seeder of zero agriculture, depending on the speed of movement of the machine and tractor unit for accurate dosing of seeds and mineral fertilizers.

7. To justify the parameters of the rolling device for compacting the soil after applying fertilizers and seeds.

8. Cost calculation and assessment of potential savings.

9. Analysis of the cost of production and implementation of the proposed seeder.

10. Prepare documentation of a zero-tillage planter for subsequent commercialization of the project.

The results obtained and the novelty: (no more than 200 words)

Zero tillage systems on seeders will allow you to add both seeds and seeds in combination with granular fertilizers. The method of applying granular fertilizers together with seeds is determined by the design of the coulters used by the zero tillage system. The distribution of granular fertilizers depends on the location of the seeds. The introduction of granular fertilizers and seeds to different depths is carried out by disc coulters. The technological process of the proposed sowing method is carried out by simultaneously embedding tuks of granular fertilizers to a greater depth than the seeds of the sown crops, i.e. a multi-level method of embedding tuks and seeds into the soil. The developed new two-disc coulter is designed for sowing seeds in a horizontal strip with a width of 12 cm, and granular fertilizers are 2 cm more than the specified depth of seed embedding and at the same time ensures the location of tuks in the middle of the strip.

Expected results:

1. Development of a working body with reasonable parameters that ensures the delay of seeds in the wavy seedbed after their exit from the seed duct.

2. Reasonable parameters of the disc coulter ripper having the ability to go deep to the desired depth and at the same time minimizing traction resistance.

3. Development of a six-row seeder for zero farming with a parallel mechanism for the working body.

4. Development of a group of seed ducts providing seed supply from a dosing device to a wavy seedbed.

5. Development of a prototype of a six-row zero-farming seeder for conducting field experiments.

6. Development of an automated system with a touch screen of a six-row zero-farming seed drill with precise dosing of seeds and mineral fertilizers depending on the speed of the machine and tractor unit.

7. Reasonable parameters of the rolling device after applying fertilizers and seeds to the soil.

8. Registration of at least one patent for an invention (including a positive decision on it) at the National Institute of Intellectual Property of the Republic of Kazakhstan.

9. Publication of one scientific article (or) review in peer-reviewed scientific publications indexed in the Science Citation Index Expanded and included in the 1st (first) and (or) 2nd (second) quartile by impact factor in the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 65.

10. The dissemination of the results of the program will be carried out by publishing articles in scientific publications and through the mass media. New knowledge and developed scientific and methodological foundations for the creation of a zero-farming seeder will be used for the further development of agricultural science, and will also become an incentive for the development of agricultural engineering and agricultural production in the Republic of Kazakhstan.

11. Prepared documentation of the zero farming seeder for the subsequent commercialization of the project.

12. The implementation of the project will allow to train at least two young scientists, including a PhD and a Master of agriculture.

Degree of implementation: ________________________________________________

List of published works within the framework of the project: (with indication of DOI, ISBN)

… _____________________________________________________________________

Name of the project / program topic: AP13268821 «Genetic mechanisms of resistance to mastitis by PRL and BLG genes in Holstein cattle»

The name of the priority area of science development for which the application is submitted 5. Sustainable development of the agro-industrial complex and safety of agricultural products.

The name of the specialized scientific research area: 5.2 Ensuring veterinary safety

Scientific director of the project/program: Kuzhebayeva Ulbosyn, master of veterinary sciences

The implementation period, its duration in months. 05/01/2022 – 12/31/2024, 32 months.

The total amount of funding, and by year: 19 000,00 thousand tenge,

2022 year – 3 000,00 thousand tenge;

2023 year – 8 000,00 thousand tenge;

2024 year – 8 000,00 thousand tenge.

Objects of research, development or design: Holstein cattle (at least 200 heads).

The purpose of the project / program: to establish the nature of the association of polymorphism of prolactin (PRL) and beta-lactoglobulin (BLG) genes of Holstein cattle with resistance to mastitis and to assess the prospects of their use as genetic markers for breeding programs.

Project / program objectives:

1. To form an experimental group of animals of the Holstein breed, to carry out the selection of biomaterial

2. To isolate DNA from the selected biomaterial and conduct its qualitative and quantitative analysis

3. Optimize the PCR procedure for DNA typing of animals by the prolactin (PRL) gene

4. Optimize the PCR procedure for conducting DNA typing of animals by the beta-lactoglobulin (BLG) gene

5. Establish animal genotypes by prolactin (PRL) gene

6. To establish animal genotypes by beta-lactoglobulin (BLG) gene

7. To analyze the genetic structure of the Kazakh population of the Holstein breed by the prolactin (PRL) gene

8. To analyze the genetic structure of the Kazakh population of the Holstein breed by the beta-lactoglobulin (BLG) gene

9. To determine the nature of the association of polymorphic variants of the PRL gene with resistance to mastitis

10. To determine the nature of the association of polymorphic variants of the BLG gene with resistance to mastitis

11. To analyze paired combinations of prolactin (PRL) and beta-lactoglobulin (BLG) genes with resistance to mastitis

12. To develop and scientifically substantiate a system of early assessment of hereditary resistance in Holstein cows to mastitis

13. To develop veterinary and hygienic recommendations for the breeding of Holstein cattle, taking into account the genotype of animals to increase their resistance to mast

The results obtained and the novelty: (no more than 200 words) As a result of the research, an experimental group of Holstein breed animals was formed, DNA was isolated from hair follicles, their qualitative and quantitative analysis was carried out, and the PCR technique for DNA typing of animals by PRL and BLG genes was optimized. The genotypes of animals according to the PRL and BLG genes were established, the genetic structure of the Kazakh population of the Holstein breed according to the PRL and BLG genes was analyzed, and the nature of the association of polymorphic variants of the PRL and BLG genes with mastitis resistance was revealed, the association of paired combinations of the PRL and BLG genes with mastitis resistance was analyzed, an early detection system was developed and scientifically substantiated assessment of hereditary resistance in Holstein cows to mastitis.

Expected results:

- optimized the PCR formulation technique for conducting DNA typing of animals using the PRL and BLG genes;

- animal genotypes have been established according to the PRL and BLG genes;

- the analysis of the genetic structure of the Kazakh population of the Holstein breed according to the PRL and BLG genes was carried out;

- the nature of the association of polymorphic variants of the PRL and BLG genes with resistance to mastitis was revealed;

 The association of paired combinations of PRL and BLG genes with mastitis resistance was analyzed;

- a system of early assessment of hereditary resistance in Holstein cows to mastitis has been developed and scientifically substantiated;

- veterinary and hygienic recommendations have been developed for the breeding of Holstein cattle, taking into account their genotype to increase their resistance to mastitis.

Degree of implementation: As a result of the research, a system for early assessment of hereditary resistance to mastitis in Holstein cattle has been developed, as well as recommendations for breeding Holstein cattle, taking into account their genotype, to increase their resistance to mastitis.

List of published works within the framework of the project: (with indication of DOI, ISBN)

1 Beishova I.S., Belaya A.V., Yuldashbayev Y.A., Chuzhebayeva G.D., Ulyanov V.A., Ulyanova T.V., Kovalchuk A.M., Kuzhebayeva* U.Zh., Namet A.M. Genetic polymorphism of prolactin and nitric oxide synthase in Holstein cattle // Veterinary World. - 2023. - Vol. 16(1). – P.161-167. (Percentile Journal CiteScore (Scopus) 2023 – 82-y, quartile Journal web of Science Core Collection-Q2,) https://doi.org/10.14202/vetworld.2023.161-167 The author of the correspondence (eng)

2 Beishova I.S., Kovalchuk A.M., Kuzhebayeva U.Zh., Ulyanova T.V., Ulyanov V.A., Ginayatov N.S., Dushaeva L.Zh., Agisheva E.R. Optimization of the PCR formulation technique for determining resistance to mastitis in cattle // Scientific and practical journal "Animal Husbandry and veterinary medicine". - Gorky, 2023. – V.1(48). – P. 56-61. https://elc.baa.by/upload/jivotnovodstvo-i-vet/jivotnovodstvo-1-2023-48.pdf (rus)

3 Kuzhebayeva U.Zh., Beishova I.S. The influence of alleles of the PRL gene in Holstein cows on resistance to mastitis // Scientific achievements of genetics and biotechnology in veterinary medicine and animal husbandry: a collection of materials of a scientific and practical conference with international participation. – Yekaterinburg: FGBNU Urfanits Ural Branch of the Russian Academy of Sciences, April 27, 2023 - P.105-111. https://uralnivi.ru/images/file/.pdf  (rus)

4 Kuzhebayeva U.Zh., Beishova I.S., Ulyanova T.V., Ulyanov V.A., Kovalchuk A.M., Agisheva E.R. Optimization of the process of genotyping cows with mastitis by the PCR-PDRF method on the beta-lactoglobulin gene // Materials XXIII international scientific and practical conference."Science, Research, education: Development trends", April 14, 2023. - Supplement No. 2 to the journal No. 2 (71) "Science and Education". - Uralsk, - 2023 – P. 307-316. https://elib.wkau.kz/wp-content/uploads/2024/04/nauka-i-obrazovanie-№2-2prilozhenie-2023.pdf (kaz)

5 Agisheva E.R., Kuzhebayeva U.J. Resistance to mastitis in cattle // Collection of materials of the International scientific and practical conference of students "The way to science - 2023!" – Uralsk: West Kazakhstan Agrarian Technical University named after Zhangir Khan, April 12, 2023 - Volume 1. – pp. 13-17. https://wkau.edu.kz/wp-content/uploads/2023/08/ot-redaktora-29-05-sbornik-2023-stud-konf-tom1-1.pdf (kaz)

6 Beishova I.S., Belaya E.V., Kuzhebayeva* U.Zh., Ulyanova T.V., Ulyanov V.A., Beishov R.S., Ginayatov N.S., Kovalchuk A.M., Kharzhau A., Sidarova A.Zh. Association of polymorphic variants of prolactin (PRL) and beta-lactoglobuliin (BLG) genes with resistance/susceptibility to mastitis in Holstein cows // Brazilian Journal of Biology. – 2024. – Vol. 84. – P. e284961-1– e284961-9. https://doi.org/10.1590/1519-6984.284961 (CiteScore Magazine Percentile (Scopus) 2023– 59th). The author of the correspondence (eng)

7 Kuzhebayeva U. Zh., Beishova I. S., Belaya A.V. Association of polymorphic variants of the BLG gene with resistance to mastitis in cattle // sbornik materials international scientific and Practical Conference "science, research, education: trends in development", dedicated to the 125th anniversary of the Academy of Sciences K. I. Satpayeva. - Uralsk: Zhangir Khan WKATU, April 12, 2024 - No. 2 (75) addition to the scientific and practical Journal of Zhangir Khan WKATU "Science and education",-2024. - No. 1 - p. 135-144. https://wkau.edu.kz/wp-content/uploads/2024/10/sbornik-pps-24.07.2024-4.pdf (rus)

8 Kuzhebayeva U.Zh., Beishova I.S., Belaya E.V. Veterinary and hygiene recommendations for breeding Holstein cattle, considering the genotype of the polymorphic PRL gene, to increase their resistance to mastitis. // Recommendations. – Uralsk, 2024. – 18 p. ISBN 978-601-319-522-3 (rus)

9 Kuzhebayeva U.Zh., Beishova I.S., Belaya E.V. Veterinary and hygiene recommendations for breeding Holstein cattle, considering the genotype of the polymorphic BLG gene, to increase their resistance to mastitis. // Recommendations. – Uralsk, 2024. – 17 p. ISBN978-601-319-523-0 (rus)

Name of the project / program topic: AP23486643 «Increasing the efficiency of moldboard plows during basic tillage».

The name of the priority area of science development for which the application is: 6. Sustainable development of the agro-industrial complex.

The name of the specialized scientific research area: 6.8. Technical support and modernization of agro-industrial complex.

Scientific director of the project/program: Beket Nuralin, doctor of technical sciences, professor.

The implementation period, its duration in months. 01.01.2024 - 31.12.2026 year, duration 36 month.         

The total amount of funding, and by year: 42 730,831 thousand tenge,

2024 year – 15 419,283 thousand tenge;

2025 year – 12 413,303 thousand tenge;

2026 year – 14 898,245 thousand tenge.

Objects of research, development or design: The development and justification of the parameters of a rotary plow for smooth plowing is the main object of research.

The purpose of the project / program: To develop and justify the design parameters and operating modes of a rotary plow for smooth plowing in order to increase the efficiency of tillage in modern conditions of Kazakhstan.

Project / program objectives:

1. Justification of the economic efficiency of smooth plowing during basic tillage;

2. Justification of the technological scheme of the rotary plow for smooth plowing;

3. Development of the frame design and working bodies of the rotary plow;

4. Study of the influence of design parameters and operating modes of the rotary plow on the quality of tillage;

5. Study of the influence of the plow operating modes on the performance of the unit;

6. Creation of a prototype of a rotary plow with rotary working bodies equipped with symmetrical diamond-shaped dumps;

7. Comparative experimental verification of the operation of serial and rotary plows during basic tillage;

8. Economic evaluation of the efficiency of the rotary plow;

9. Analysis of the cost of production and implementation of a new rotary plow for smooth plowing;

10. Preparation of technical documentation for further commercialization of rotary plow production with symmetrical diamond-shaped dumps for smooth plowing.

The results obtained and the novelty: The results obtained will allow us to expand the theoretical and practical aspects of studying the theory and design of tillage machines.

Scope and target consumers of expected results. All individuals and organizations involved in agricultural engineering will be interested in these studies, incl. scientists, graduate students, doctoral students and teachers.

The influence of the expected results on the development of the main scientific direction and related areas of science and technology. Currently, insufficient attention is paid to smooth plowing due to the lack of tillage machines. The results obtained will complement the scientific position on agriculture and agricultural mechanics.

Applicability and possibility of commercialization of the obtained scientific results. Conducting this study will not only provide answers to the effectiveness of smooth plowing, but will also allow the development of scientific recommendations for the development of soil-cultivating machines and will give impetus to further research.

Social, economic, environmental, scientific, technical, multiplicative and (or) other effect of the project results with justification. The implementation of this project is of great national economic importance; it will significantly enrich the scientific, practical and theoretical base on plowshare plows, give impetus to the development of other projects in this area, and stimulate the work of young scientists and specialists in the field of designing rotary plows.

Expected results: As a result of the work done, the following results will be obtained:

● Development of the design of the frame and rotating mechanism of the plow; and determination of rational parameters of a rotary plow;

● Development of the design of a stand, a shoe with field boards and a symmetrical diamond-shaped blade;

● Selection of rational parameters and operating modes of the rotary plow for smooth plowing in accordance with agrotechnical requirements with the lowest energy consumption;

● Development of technical specifications, scientific, technical and design documentation for a prototype rotary plow with symmetrical diamond-shaped moldboards for the subsequent commercialization of smooth plowing during basic soil cultivation;

● Studying the influence of smooth plowing on the quality of tillage, increasing the productivity of the unit and reducing specific energy consumption;

● Studying the analysis of the efficiency of smooth plowing with a rotary plow;

● Introduction of a prototype rotary plow into agriculture and agricultural engineering;

● Registration of a patent at the National Institute of Intellectual Property of the Republic of Kazakhstan.

Degree of implementation: ________________________________________________

List of published works within the framework of the project: (with indication of DOI, ISBN)

1. _____________________________________________________________________
2. _____________________________________________________________________
3. _____________________________________________________________________

… _____________________________________________________________________

Name of the project / program topic: Development of a set of models for the digital transformation of agro-industrial enterprises, considering the adaptation of business processes to changing consumer demands and the global economic situation.

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: Bioinformatics and digitalisation in the agro-industrial complex system

Scientific director of the project/program: Rustenova Elvira, candidate of economic sciences, associate professor

The implementation period, its duration in months. 09.09.0024 - 31.12.2024 year, duration 28 month.         

The total amount of funding, and by year: 79 141 093,25 thousand tenge,

2024 year – 29 635 590,25 thousand tenge;

2025 year – 26 017 027 thousand tenge;

2026 year – 23 488 476 thousand tenge.

Objects of research, development or design:

Digital transformation of agro-industrial enterprises in Kazakhstan

The purpose of the project / program: Development of theoretical and methodological substantiation of the process of digital transformation of agro-industrial enterprise of Kazakhstan on the basis of management decision-making in the conditions of adaptation to the requirements of consumers, regulators and economic conjuncture.

Project / program objectives:

The results obtained and the novelty:

Expected results:

As a result of the realization of the set tasks, the formation of valuable scientific results is expected, representing a systematic and comprehensive analysis of the digital transformation of the agro-industrial complex on the example of agro-enterprise of the livestock industry.

Based on the realization of the set objectives, the following results are expected to be obtained:

1. a comprehensive assessment of the digital transformation potential for agro-industrial enterprises in Kazakhstan will be developed, including analysis of the current state, identification of potential opportunities and barriers, and development of strategic directions for digitalization.

2. a detailed analysis of key business processes and management decisions required for digital transformation will be performed. Key areas for the implementation of digital technologies and innovations will be identified.

3. standards and procedures will be developed to manage the digital transformation process, based on a scientific approach and study of best international practices, including recommendations for the introduction and adaptation of digital technologies.

4. Digital transformation models will be created for each process group of agrocluster enterprises using the method of network analysis according to T. Saaty's methodology. The models will cover production, logistics and administrative processes.

5. A generalized model of digital transformation will be developed and successfully tested on the basis of «KTK-888» LLP. The model includes a new management decision-making system adapted to digital technologies.

6. A cost-effectiveness justification will be prepared and recommendations on the size of government subsidies to stimulate digital transformation in the livestock sector will be proposed.

7. Two scientific articles or reviews will be prepared and published in a peer-reviewed scientific publication indexed in Social Science Citation Index, Arts and Humanities Citation Index and (or) Web of Science database and (or) having a CiteScore percentile in Scopus database not less than 35 (thirty-five). In addition, 5 articles will be published in domestic editions recommended by the Committee for Quality Assurance in the Field of Science and Higher Education of the Ministry of Science and Higher Education of the Republic of Kazakhstan.

8. Based on the results of the study, a monograph in Russian is expected to be prepared

9. The results of the study will be disseminated among potential users, the scientific community and the general public through participation in international conferences and scientific and methodological workshops. It is also envisaged to develop proposals and recommendations for the Ministry of Agriculture, Ministry of Digital Development, Innovation and Aerospace Industry.

10. Expected scientific and socio-economic effect. It has to be stated that currently there are practically no works devoted to a full-fledged comprehensive study of the problems of forming business models of the agro-industrial sector in the current conditions of digital transformation challenges. All the planned scientific results are new, are not reduced to insignificant modifications of previously conducted research, are in line with the main world trends, will have an important scientific and socio-economic significance. They can be used in the development of strategic and programme documents on sustainable development, digitalisation and increasing the competitiveness of the agro-industrial sector, development projects of agro-industrial companies.

11. Applicability and/or commercializability of the obtained scientific results. The results of the conducted research provide valuable information materials that can be very useful in the implementation of the development strategy of the agro-industrial complex (AIC) of the Republic of Kazakhstan

Degree of implementation:

List of published works within the framework of the project:

Name of the project / program topic: АР23487474 «Development of a universal planting complex for garden and forest crops with an automated fertilizer application system».

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex.

The name of the specialized scientific research area: Technical support and modernization of agro-industrial complex.

Scientific director of the project/program: Amangeldy Sarsenov, PhD

The implementation period, its duration in months. 01.01.2024 - 30.12.2026 year, duration 36 month.         

The total amount of funding, and by year: 120 000, 000 thousand tenge,

2024 year – 34 000, 000 thousand tenge;

2025 year – 43 000, 000 thousand tenge;

2026 year – 43 000 000 thousand tenge.

Objects of research, development or design: The technological process of planting seedlings of forest and fruit crops.

The purpose of the project / program: Improving the technology of planting seedlings of forest and fruit crops through the development of a universal planting complex with an automated control system to provide seedlings with nutrients in the short and long term.

Project / program objectives:

1. Development of the technological process of the universal landing complex.

2. Development and justification of the parameters of a universal active working body for creating a landing place (trench) under the seedlings.

3. Virtual simulation of the operation of a three-dimensional model of a universal active working organ to optimize the parameters of the working organ, I minimize research costs.

4. Creation and field testing of an experimental model of a universal active working organ.

5. Development and justification of the parameters of the distributor of organic and mineral fertilizers.

6. Integration of the distributor of organic and mineral fertilizers into the base of the universal planting complex.

7. Layout of the universal landing complex.

8. Commissioning.

9. Field testing of the universal landing complex.

10. Research on the quality of planting seedlings and the degree of survival.

11. Assessment of the economic efficiency of the developed technical means.

12. Preparation of technical documentation for the commercialization of the production of a universal planting complex for garden and forest crops with an automated fertilizer application system for short- and long-term feeding of the root system of seedlings.

The results obtained and the novelty: (no more than 200 words)

The developed universal planting complex will create the necessary planting space for different varieties and types of seedlings, and dose the necessary amount of fertilizers to the location of their root system. Mineral fertilizers will promote the survival and activation of seedlings, and organic fertilizers will ensure the availability of nutrients during growth and fruiting (short-term and long-term feeding of seedlings). New knowledge and developed scientific and methodological foundations obtained during the creation of a universal planting complex of garden and forest crops with an automated fertilizer application system will be used for the further development of agricultural science, and will also become an incentive for the development of agricultural engineering and agricultural production in the Republic of Kazakhstan.

Expected results:

1. The technological process of the universal landing complex.

2. Optimal parameters of the universal working body for creating seating.

3. The results of virtual modeling of a three-dimensional model of a universal working organ.

4. An experimental model of the first module - a mechanism for creating a trench for planting seedlings.

5. Optimal parameters of the distributor of organic and mineral fertilizers.

6. An experimental model of the second module - an aggregate for the placement of organic and mineral fertilizers.

7. A universal landing complex ready for testing.

8. Results of field trials of the universal landing complex.

9. Technical documentation for the prototype of the universal landing complex.

10. The introduction of a prototype universal planting complex in agriculture and rural engineering.

11. Registration at the National Institute of Intellectual Property of the Republic of Kazakhstan of at least 1 patent for an invention (including a positive decision on it).

12. Publication of one scientific article in peer-reviewed scientific publications indexed in the Science Citation Index Expanded Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 65.

13. The implementation of the project will allow to prepare a PhD.

Degree of implementation: ________________________________________________

List of published works within the framework of the project: (with indication of DOI, ISBN)

1. _____________________________________________________________________
2. _____________________________________________________________________
3. _____________________________________________________________________

… _____________________________________________________________________

Project/program topic name: AP26199343 Epizootic monitoring of cattle respiratory diseases of infectious ethics in the West Kazakhstan region and development of hyperimmune serum against pasteurellosis

Name of the priority area of ​​scientific development for which the application is submitted. Sustainable development of the agro-industrial complex

Name of the specialized scientific area of ​​research:

1. Veterinary science

Scientific director of the project/program: Utegen Taubayev, doctor of veterinary sciences, professor.

Implementation period, its duration in months. 01.01.2025 – 31.12. 2027. 36 months.

Total funding, and by year: 115166789 tenge,

2025 - 38226980 tenge,

2026 - 39590849 tenge,

2027 - 37348960 tenge.

Objects of research, development or design: farm animals, laboratory animals, reference strains, etc.

Project/program objective: Development of a system for monitoring the epizootic situation of respiratory diseases of infectious etiology in cattle in the West Kazakhstan region and creation of a hyperimmune serum against pasteurellosis. Objectives of the project/program:

1) Study of epizootic situations of bacterial infectious diseases of animals in the West Kazakhstan region, retrospective statistical analysis of morbidity, nosological profile of infectious diseases of bacterial etiology of animals (cattle) and analysis of the obtained data.

2) Determine the taxonomic position of pathogens of bacterial diseases, identify the leading etiological agents, their quantitative and qualitative spectrum in the long-term aspect and establish the incidence rate of bacterial diseases of animals (cattle), their long-term dynamics and growth rates; assess the severity of the epizootic situation using the epizootic index.

3) Development of NTD for hyperimmune serum against pasteurellosis, its implementation in veterinary practice

4) Evaluation of the effectiveness of existing veterinary and sanitary measures for the prevention and control of the spread of infectious diseases.

5) Development of recommendations for the timely use of preventive and therapeutic measures to prevent the spread of respiratory infections. Obtained results and novelty: (no more than 200 words)

1) Respiratory diseases of young cattle (cattle) are an acute problem all over the world.

2) Creation of stable well-being of the territory of the Republic of Kazakhstan for especially dangerous infections and ensuring biological safety is an important task for improving the socio-economic situation and strengthening national security.

3) Among the modern priorities in the field of food and biological security of the country, a special place belongs to infectious diseases of humans and animals.

Expected results: A retrospective statistical analysis of morbidity will be carried out, the epizootic situation, the nosological profile of respiratory diseases of cattle of infectious etiology in the West Kazakhstan region will be studied

An interim report will be prepared and submitted. One article will be published in a scientific publication recommended by the KOKSNVO. Laboratory tests will be conducted to create a hyperimmune serum based on the isolated strains and to test specificity and effectiveness

Field tests will be conducted on farms in the West Kazakhstan region where outbreaks of pasteurellosis have been registered

An interim report will be prepared and submitted. One article will be published in a scientific journal recommended by the KOKSNVO and 1 article in peer-reviewed scientific journals indexed in the Science Citation Index Expanded and included in the 2nd (second) quartile by impact factor in the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 65 (sixty-five)

Dosages and application regimens will be optimized based on the results of field tests.

Degree of implementation: the scientific and technical effect of the project results consists in the creation of an effective drug, widely used in production, the development of scientific and technical knowledge and technological sectors of the economy

List of published works within the framework of the project: (indicating DOI, ISBN)

1. _____________________________________________________________________

2. _____________________________________________________________________

3. _____________________________________________________________________

Name of the project / program topic: АР00000000 «Study of economically useful traits and characteristics of the gene pool of cattle of the Kazakh white-headed breed by resequencing and transcriptomic analysis».

The name of the priority area of science development for which the application is submitted 6. The science of life and health

The name of the specialized scientific research area: 6.2 Innovative biological research to increase the productivity and sustainability of plant varieties and animal breeds in agriculture

Scientific director of the project/program: Tatyana Ulyanova, PhD

The implementation period, its duration in months. 01.02.2023 – 31.12.2025, duration 35 months.

The total amount of funding, and by year: 99 350,0 thousand tenge:

 2023 – 27 750,0 thousand tenge; 

 2024 – 35 800,0 thousand tenge;

 2025 – 35 800,0 thousand tenge.

Objects of research, development or design: Cattle of the Kazakh white-headed breed _____________________________________________________________________________

The purpose of the project / program: conducting resequencing and transcriptomic analysis of cattle of the Kazakh white-headed breed in the Republic of Kazakhstan, characterization of the gene pool, identifying specific genetic variants under selection pressure associated with economically useful traits.

Project / program objectives:

1. Selection and description of a sample of the Kazakh white-headed breed and selection of biological material;

2. Genome-wide resequencing of perspective individuals and bioinformatic data processing;

3. Analysis of the heterozygosity index in the genomes of the Kazakh white-headed breed with other breeds;

4. Identification of SNP polymorphisms, INDEL polymorphisms, CNV index and structural variations in the genome of the Kazakh white-headed breed;

5. Identification of informative genome variants responsible for economically useful traits;

6. Determination of informative polymorphisms and creation of a genetic database of variations of the Kazakh white-headed breed;

7. Determination of informative miRNA profiles in the Kazakh white-headed breed;

8. Development of scientifically-based methodological proposals to assess the state of the gene pool, preserve and improve the genetic diversity of cattle of the Kazakh white-headed breed.

The results obtained and the novelty: (no more than 200 words)

An experimental group of Kazakh white-headed cattle was formed in the amount of 15 bulls (West Kazakhstan region, Bokeyordinsky district, Burli village) and biomaterial from animals was selected. A total of 903459044 readings were obtained, of which 895309555 were successfully mapped to the reference genome, according to the criteria for sequencing quality control. As a result of the study, it was found that the expected and observed heterozygosity of the Kazakh white-headed breed was 0.402 and 0.398, respectively. Inserts and deletions (INDEL) were identified in the genome of the Kazakh white-headed cattle breed, the sizes of which ranged from 1 to 61 base pairs.As a result of the study, 21707 variants were characterized, of which 9935 (45.8%) turned out to be new, and 11772 (54.2%) corresponded to previously known variants. Most of the detected variants (55%) were located in the intronic regions of genes, which is typical for many species of organisms. Among the variants located in the coding regions of genes, 55% were missense mutations that can change the structure and function of proteins, and 41% are synonymous substitutions that do not affect the amino acid sequence.

Expected results: ________________________________________________________

The SNP and genes involved in the formation of economically useful traits of the Kazakh white-headed breed will be identified in the genome, specific genetic variants will be found and recommended for use in breeding. Unique miRNA transcription profiles of the Kazakh white-headed breed will be revealed. Eventually, recommendations for assessment of the genetic potential, preserving and improving the genetic resources of the Kazakh white-headed breed will be developed.

Degree of implementation: The research results will become the basis for the development of breeding programs and effective management of the breeding process in beef cattle breeding, conservation and improvement of genetic resources for the purpose of socio-economic development on the scale of the Republic of Kazakhstan.

List of published works within the framework of the project: (with indication of DOI, ISBN)

1 Ulyanova T. V., Beishova I. S., Shamshidin A. S., Kovalchuk A.M., Kulbaev R.M., Beishov R.S. Reclamation of the full genome of the large rogue Scota of the Kazakh white blood cell / Scientific and practical Journal WKATU named after Zhangir Khana "Science and education". - 2024. - №3-2 (76). - P.130-140. https://doi.org/10.52578/2305-9397-2024-3-2-130-140

Name of the project topic: AP23488151 «Progressive resource-saving technologies for the production of meat and hatching eggs of musk ducks».

The name of the priority area of science development for which the application is submitted: 6. «Sustainable development of the agro-industrial complex and safety of agricultural products»

The name of the specialized scientific research area: 5. «Development of intensive animal husbandry».

Scientific director of the project: Alzhan Shamshidin, candidate of agricultural sciences.

The implementation period, its duration in months: 03.01.2024 – 31.12.2026 (36 months).

The total amount of funding, and by year: 120000000 tg.

2024 г. – 34000000 tg;

2025 г. – 43000000 tg;

2026 г. – 43000000 tg;

Objects of research, development or design:

The source material for the work will be musk ducks and the resulting mulard (English mulard, moulard; derived from the English «muscovy duck», «musky duck» and English «mallard», «mallard»), that is, an interspecific hybrid obtained by crossing drakes of musk ducks with domestic ducks of the Peking white breeds.

The purpose of the project:

The aim of the project is to develop advanced resource–saving technologies for the production of meat and incubation eggs of musk ducks in the West Kazakhstan region.

Project objectives:

To achieve this, scientific and experimental research will be conducted by solving the following and interrelated tasks that require consistent implementation:

1. To study the food supply and chemical composition of the main types of waterfowl feed in the Western region;

2. To form experimental groups of young musk ducks;

3. To develop formulations of musk duck feed mixture;

4. To study the growth and development, safety, and productive indicators of young musk ducks;

5. To study the economically useful, productive and reproductive qualities of musk ducks;

6. To lay eggs for incubation, to study the biological control and hatchability of musk duck eggs;

7. To study the main zootechnical indicators of the resulting young;

8. Get mulards from the musk duck drake and the female Peking white;

9. To form experimental groups of young musk ducks and mulards and to make balanced diets for experimental groups;

10. To study the growth and development, preservation, and productive indicators of young musk ducks and mulards;

11. To study the meat productivity and slaughter indicators of young musk ducks and mulards;

12. To carry out an organoleptic assessment and study the morphological and chemical composition of meat of musk ducks and mulards;

13. Calculate the economic efficiency of the research results.

The results obtained and the novelty:

The scientific novelty of the work. For the first time in the West Kazakhstan region, progressive resource–saving technologies for the production of meat and incubation eggs of waterfowl in the West Kazakhstan region will be developed. Research will be conducted on the production of mulards, on the study of productive, economically useful, reproductive, slaughter qualities of birds, and incubation of eggs of musk ducks.

The practical significance of the project lies in the fact that the developed progressive resource-saving technologies for the production of meat and hatching eggs of musk ducks will allow us to offer additional reserves for increasing meat productivity and the efficiency of hatching eggs production, ensuring high efficiency of duck breeding, in particular, musk ducks and significantly increase the efficiency, competitiveness and productivity of the poultry industry.

Expected results:

The food supply and chemical composition of the main types of waterfowl feed in the Western region will be studied. Monitoring of microclimatic parameters will be carried out with automatic devices for monitoring microclimate parameters;

Hatching eggs and waterfowl will be purchased. Experimental groups of young musk ducks will be formed;

Formulations of feed mixtures for musk ducks will be developed;

The growth and development, safety, and productive indicators of young musk ducks will be studied;

The economically useful, productive and reproductive qualities of musk ducks will be studied;

Eggs will be laid for incubation, biologically controlled using an ovoscope and the hatchability of musk duck eggs will be studied. An egg quality detector will be purchased to study the weight, shell strength, yolk index, and shell thickness.

The main zootechnical indicators of the resulting young will be studied;

Mulards will be obtained from the drake of the musk duck and the female of the Beijing white;

Experimental groups of young musk ducks and mulards will be formed and balanced diets will be compiled with the addition of various compound feeds such as Start, Growth, Finish and dietary supplements;

The growth and development, preservation, and productive indicators of young musk ducks and mulards will be studied;

Meat productivity and slaughter indicators of young musk ducks and mulards will be studied. An infrared analyzer will be purchased for analysis;

An organoleptic assessment will be carried out and the morphological and chemical composition of the meat of musk ducks and mulards will be studied;

The economic efficiency of the research results will be calculated.

At least 2 (two) will be published articles and (or) reviews in peer-reviewed scientific publications indexed in the Science Citation Index Expanded of the Web of Science database and (or) having a CiteScore percentile in the Scopus database of at least 50 (fifty); as well as at least 1 (one) article or review in a peer-reviewed foreign or domestic publication recommended by the Committee for Quality Assurance in Science and Higher Education of the Ministry of Science and Higher Education of the Republic of Kazakhstan for the publication of the main results of scientific activities.

The objectives of this project directly correspond to the strategic objectives of the Republic of Kazakhstan in the field of agriculture and food security. Improving the quality and efficiency of poultry production contributes to the development of poultry farming and supports the country's strategic plans to provide food to the national market of Kazakhstan.

It is planned to publish 1 (one) monograph. The monograph will present an original scientific work and is based on the generalization of the results of its own research within the framework of the project.

As part of the Project, the following scientific, technical, and design documentation will be received:

- 1 (one) methodological recommendation will be developed.

Based on the results of the study, it will be implemented into production and will be confirmed by 1 (one) Implementation Act indicating the achieved economic effect and recommendations for implementation.

Degree of implementation:

The research results of this project can be used in large and small farms, peasant farms, private subsidiary farms and private farmsteads in various regions of Kazakhstan.

The results will meet the social demand for high-quality meat and hatching eggs, ensuring food safety and supporting the food industry. The economic and industrial interest in the results of the program is manifested in increasing the competitiveness of local producers and their ability to compete in the global market.

As a result of the production and consumption of environmentally friendly food products, both social and economic effects will be achieved, which is expressed for consumers – in improving the health of the population, with an increase in consumption of environmentally friendly products, for entrepreneurs – in the possibility of obtaining additional income, while increasing the reserves of meat and poultry meat productivity, for the state as a whole – achieving high indicators characterizing the health of the population.

List of published works within the framework of the project:

Name of the project / program topic: AP14870980 «Study of specific features of the genetic structure of sturgeon fish and their hybrids grown in closed water supply installations».

The name of the priority area of science development for which the application is submitted 6. Life and Health Science

The name of the specialized scientific research area: 6.1 Study, conservation and rational use of genetic resources of Kazakhstan. Innovative approaches to environmental monitoring and protection.

Scientific director of the project/program: Nurbek Ginayatov, PhD, associate professor.

The implementation period, its duration in months. 01.07.2022 – 31.12.2024 year, duration 30 month.         

The total amount of funding, and by year: 78 000 thousand tenge,

2022 year – 12 000 thousand tenge;

2023 year – 33 000 thousand tenge;

2024 year – 33 000 thousand tenge.

Objects of research, development or design: individuals of sturgeon fish species and their hybrids grown in the CWSI.

The purpose of the project / program:  Characterize the allelofond of sturgeon populations and their hybrids reared in conditions of closed water supply facilities, to develop recommendations aimed at preserving the genetic diversity of fish from the breeding stock on the basis of molecular genetic identification methods.

Project / program objectives:

– Form groups of sturgeon fish, perform chipping for identification, take samples of biological material;

– Isolate DNA from biological material, conduct qualitative and quantitative assessment of isolated DNA material;

– Carry out STR-typing on a genetic analyzer;

– Draw up a genetic profile for each of the studied sturgeon based on the results of STR typing

– To reveal the frequency of alleles of the studied STR-loci in individuals from the recovery brood stock;

– To characterize genetic structure of the studied sturgeon populations and their hybrids;

– To carry out comparative analysis of genetic diversity of the domestic populations of sturgeon fishes with the foreign data, to estimate the level of differentiation between the samples;

– To determine specific features of genetic structure and state of gene pools of the studied sturgeon populations by microsatellite markers;

– To develop recommendations on preserving the genetic diversity of the breeding stock of sturgeons reared in closed water supply facilities.

The results obtained and the novelty: (no more than 200 words) Experimental groups of sturgeon fish have been formed, kept in conditions of closed-loop water supply installations. Subcutaneous microchips in a T-VAS Datamars needle were installed in selected sturgeon specimens (n=276). The initial biological material was selected for microsatellite analysis by taking ectodermal tissue – a fragment of the pectoral fin of sturgeons by the method of lifetime selection of biological samples, without using the decapitation technique. To qualitatively and quantitatively evaluate the isolated DNA from biological material, its concentration was measured on an Agilent Cary 60 spectrophotometer. The average DNA concentration was 156.8 ng/µl. STR-typing of 276 individuals of sturgeon fish contained in the conditions of ultrasound was carried out on the AB 3500 genetic analyzer (AppliedBiosystem, USA). A pair of primers were used to amplify each STR locus, providing effective and highly specific PCR amplification. DNA fragments were separated by capillary electrophoresis in a polymer gel. Based on the results of STR-typing, a genetic profile was compiled for each of the studied sturgeons.

Expected results: ccording to the results of research in accordance with the requirements for industries in the field of agricultural sciences on applied research will be published at least two (2) articles and (or) reviews in peer-reviewed scientific journals, indexed in Science Citation Index Expanded base Web of Science and (or) having the percentile on CiteScore in the base Scopus not less than 35 (thirty five), not less than 1 (one) article or review in the refereed foreign or domestic edition, recommended by the CQAES and also the recommendation on conservation of genetic diversity of sturgeon fish will be developed.

The obtained results will expand the theoretical and practical aspects of improving the breeding work in fish farms by using a new approach to the study of the genetic structure of sturgeon fishes.

The target consumers of the obtained results will be organizations engaged in commercial breeding of valuable fish species, selection and breeding work in fish farming, etc.

Degree of implementation: not implemented

List of published works within the framework of the project: (with indication of DOI, ISBN)

1.  Ginayatov, N. S. Assessment of polymorphism by STR-loci of Sturgeon grown in the conditions of closed water supply facilities / Ginayatov N.S., Ulyanov V.A., Ulyanova T.V., Asylbekova S.Zh., Sidarova A.Zh. / Science and education, – Uralsk: RIO WKATU named Zhangir Khan, 2022. – V. 3 (68). – P. 122-133. https://doi.org/10.56339/2305-9397-2022-3-1-122-133 (kaz)

2.  Ginayatov N.S., STR-genotyping of sturgeon moats developing in extremities: the meaning and prospects of examples/ N.S. Ginayatov, I.S. Beishova, V.A. Ulyanov, T.V. Ulyanova, A.M. Kovalchuk, A.Zh. Sidarova // educational notes of the Kazan State Academy of Veterinary Medicine named N.E. Bauman, 2023. – V. 255 (III). – P. 116-122. https://kazanveterinary.ru/wp-content/uploads/2023/10/%D0%A2%D0%BE%D0%BC-255.pdf (rus)

3.Ulyanov V., Beishova I., Ulyanova T., Sidarova A., Ginayatov N.*, Kovalchuk A., Chuzhebaeva G., Alikhanov K., Sariyev B., Kuzhebayeva U., Nurzhanova F., Beishov R., Sabyrzhanov A. and Bexultan A. 2024 Genetic health and diversity assessment of Sturgeon species in Kazakhstan's aquaculture and natural habitats. Ger. J. Vet. Res. 4 (2): 127-138.https://doi.org/10.51585/gjvr.2024.2.0090 (CiteScore Magazine Percentile (Scopus) 2023 – 61th). The author of the correspondence (eng)

4. Ginayatov, N., Ulyanov, V., Beishova, I., Ulyanova, T.*, Sidarova, A., Kovalchuk, A., Sariyev, B., Kuzhebayeva, U., Bakhareva F., Alikhanov, K. Comparison of genetic diversity indicators in samples of artificial and natural populations of Russian sturgeon and beluga at the mount of the Ural river. Advancements in Life Sciences (accepted for publication). (CiteScore Magazine Percentile (Scopus) 2023 – 45th) The first author (eng)

5. Ginayatov N.S., Comparative assessment of the genetic diversity of sturgeon fish grown in aquaculture conditions / N.S. Ginayatov, V.A. Ulyanov, I.S. Beishova, A.M. Kovalchuk, T.V. Ulyanova, B.T. Sariev, A.Zh. Sidarova // Science and education, – Uralsk: WKATU named Zhangir Khan, 2024. – V. 3-1(76). – P.105-114. https://doi.org/10.52578/2305-9397-2024-3-1-105-114 (rus)

6. Beishova I.S., Ginayatov N.S., Ulyanov V.A., Ulyanova T.V., Kovalchuk A.M., Sariev B.T., Sidarova A.J., Recommendations for determining the genetic structure of populations of sturgeon fish species and their hybrids / Recommendation. – Uralsk: NPJSC "West Kazakhstan Agrarian and Technical University named Zhangir Khan", 2024. – 50 p. ISBN 978-601-319-528-5 (rus)

7. Beishova I. S., Ginayatov N. S., Ulyanov V. A., Sariev B. T., Ulyanova T. V., Kovalchuk a.m., Sidarova A. zh.the current state of sturgeon fish and recommendations for their conservation and restoration / Recommendation. – Uralsk: NPJSC "West Kazakhstan Agrarian and Technical University named Zhangir Khan", 2024. – 51 p. ISBN 978-601-319-529-2 (kaz)

Name of the project / program topic: BR22887106 « Application of molecular genetic methods for horse genetic resources management optimization and efficient horse breeding innovative technologies development».

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex

The name of the specialized scientific research area: Intensive livestock farming.

Scientific director of the project/program: Indira Beishova, doctor of biological sciences, associate professor.

The implementation period, its duration in months. 01.2024 - 12.2026 year, duration 36 month.         

The total amount of funding, and by year: 787 147,2 thousand tenge,

2024 year – 254 900,8 thousand tenge;

2025 year – 264 174,4 thousand tenge;

2026 year – 268 072,0 thousand tenge.

Objects of research, development or design: Kazakh horse breeds,        genetic markers associated with milk production.

The purpose of the project / program: Development of new methods and improvement of existing techniques for managing equine genetic resources and effective technologies for the production of horse breeding products

Project / program objectives:

- Development and improvement of the system for obtaining reliable pedigree records in productive horse breeding, as well as information modules for collection, storage, processing and automatic calculation of pedigree value of productive horses;

- Development of a panel of genetic markers for productive horses, allowing earlier prediction of the level of their milk productivity;

- Development of breeding and technological programs for consolidation of pedigree qualities of productive horse breeds with approbation of new breeding achievements;

- Determination of desirable exterior parameters of horses used for mare milk production;

- Development of effective methods of horse reproduction in the production of mare's milk and technology of its processing.

The results obtained and the novelty: -

Expected results:

1. A methodological guide on the principles of collection of primary breeding documentation taking into account the main breeding traits of horses of productive direction will be developed;

2. Information modules for collection, storage and processing of breeding records and calculation of breeding value of productive horses will be developed and improved;

3. A genetic bank (DNA from at least 500 dairy mares) will be created. Genotyping will be carried out using at least 80K SNPs with subsequent analysis of genetic diversity of populations;

4. Statistical analysis will be carried out to determine the relationship between single nucleotide polymorphisms and the level of milk productivity of mares;

5. A panel of genetic markers for early prediction of mare milk production will be developed;

6. Breeding groups of horses of productive direction are formed, growth and development of litter obtained from custom mating (in at least 15 farms) will be studied;

7. Breeding and genetic parameters of linear exterior traits of mares with the study of milk productivity will be determined (at least 80 animals);

8. Recommendation on technological design of koumiss farms with effective technologies of keeping, feeding and milking of mares (not less than 3 farms) will be developed;

9. Recommendations on new technologies of drying and processing of mare milk will be developed;

10. Young specialists will be involved, including at least 2 PhD students and 4 master students;

11. Within the framework of the implementation of scientific research under the program there should be published at least 2 (two) scientific publications for the whole period of research in peer-reviewed scientific editions included in quartiles (Q1, Q2, Q3) of Web of Science database or having Cite Score percentile in Scopus database not less than 30 (thirty)

12. At least 3 (three) articles will be published in peer-reviewed scientific editions indexed in Science Citation Index Expanded of Web of Science base and (or) having CiteScore percentile in Scopus base not less than 35 (thirty-five) and not less than 8 (eight) publications were published in foreign and domestic editions recommended by the Committee for Quality Assurance in the field of Science and Higher Education of the Republic of Kazakhstan;

13. Applications for creation of new breeding achievements in productive horse breeding will be submitted;

14. Publication of monographs and (or) books and (or) chapters in books by foreign and (or) Kazakhstani publishing houses;

15. Obtaining patents in foreign patent offices (European, American, Japanese) and (or) Kazakhstani or Eurasian patent office;

16. Activities on pilot implementation of the program results and (or) dissemination of knowledge and results obtained during the implementation of the program among potential users, community of scientists and the general public;

17. Scientific and technical documentation will be developed for information modules for the collection, storage and processing of breeding data, as well as for calculating the breeding value of productive horses.

Degree of implementation: -

List of published works within the framework of the project: -

Name of the project / program topic: AP23487588 Improving the prevention of piroplasmosis of cattle transmitted by ixodid ticks in the steppe, semi-desert and desert zones of West Kazakhstan region

The name of the priority area of science development for which the application is submitted Sustainable development of the agro-industrial complex

The name of the specialized scientific research area:

Veterinary medicine

Scientific director of the project/program:

Sidikhov Bekzhasar Mustakapovich, Candidate of Veterinary Sciences

The implementation period, its duration in months. 01.01.2024 – 12.31.2026-year, duration 36 months.

The total amount of funding, and by year: 119929,805 thousand tenge,

2024 – 33999,721 thousand tenge.;

2025 – 43000,0 thousand tenge.;

2026 – 42930,084 thousand tenge.

Objects of research, development or design:

pyroplasmides, ixodides, cattle

The purpose of the project / program:

To study the current epizootic situation of piroplasmidosis and ixodidosis of cattle and to develop an effective treatment and prevention regimen for piroplasmidosis and ixodidosis in various natural zones of the West Kazakhstan region.

Project / program objectives:

1. To study the distribution and species composition of ixodid ticks in the steppe, semi-desert and desert zones of West Kazakhstan region. Ticks found on cattle will be identified to species. The distribution of ticks in various natural zones of West Kazakhstan region has been determined, which is necessary for the development of preventive measures.

2. To determine seasonal dynamics of tick infestation in cattle in various natural zones of West Kazakhstan region. To determine infestation of ixodids by piroplasmids using the PCR method. Seasonal dynamics, the index of tick abundance in cattle and the infestation of ixodids by piroplasmids, necessary for the development of preventive measures, will be determined.

3. To determine the age dynamics of ixodidae infestation in cattle in various natural zones of WK region and their distribution on the body of animals, taking into account the age structure (larva - nymph - imago).

4. To study epizootic situation regarding piroplasmosis in cattle in various natural zones of WK region. The extent of invasion of cattle by piroplasmids and their type will be determined by studying blood smears and PCR, necessary for the development of preventive measures.

5. To determine the nature of the course and symptoms of piroplasmosis in cattle in various zones of WK region. The nature of the course and symptoms of the disease necessary for the development of preventive measures will be determined.

6. To determine seasonal and age-related dynamics of piroplasmosis in cattle in various zones of WK region using the PCR method. Seasonal and age dynamics of piroplasmosis in cattle will be determined, which are necessary for the development of preventive measures.

7. To determine medication effectiveness against piroplasmosis. The effectiveness of anti-pyroplasmidose medication will be determined using PCR, a complex for pathogenetic therapy of cattle will be compiled, necessary for the development of preventive measures..

8. To study the effectiveness of acaricides used against ixodids. The effectiveness of acaricides will be determined by invitro and invivo methods, necessary for the development of preventive measures.

The results obtained and the novelty: (no more than 200 words)

The seasonal dynamics of infection of cattle with ticks was determined by quarterly (winter, spring, summer and autumn) animal studies, and age-based studies of various age groups: under one year, 1-3 years, 4-5 years, 6 years and older. The collection of ticks from vegetation was carried out on the "flag". The collection of ticks from cattle was carried out with tweezers in cans with a capacity of 100 mm3. In the steppe, semi-desert and desert zones of the West Kazakhstan region, cattle are infected with ticks of the Ixodidae family, belonging to five genera and ten species of ticks. The highest infection rate was observed in spring and summer and ranged from 100 to 90%. The greatest animal infestation was recorded in the steppe zone, and the lowest in the desert zone. Index of occurrence is averaged 55%, the highest index of abundance was determined in H. detritum – 59.3±12.1, and the lowest in I. ricinus - 3.5±1.0 ex/head. Young animals under the age of one year and from 1 to 3 years old were most affected, and the index of abundance was 216.2 - 252.4 ex/head, respectively.

Novelty: the development of a rational scheme for the treatment and prevention of pyroplasmidosis, and ways to control ticks.

Expected results:

1. Distribution and species composition of ixodid ticks in cattle in the steppe, semi-desert and desert zones of West Kazakhstan region will be determined.

2. Seasonal dynamics, tick abundance index in cattle and ixodid piroplasmid infestation will be determined using the PCR method.

3. Age dynamics of ixodid infestation in cattle, the distribution of ixodids on the body of animals, taking into account age structure (larva - nymph - imago) and the total stock of ixodids in various natural zones of West Kazakhstan region will be determined.

4. The extent of invasion of cattle by piroplasmids and their type will be determined by studying blood smears and PCR in various natural zones of West Kazakhstan region.

5. The nature of the course and symptoms of piroplasmosis in cattle in various zones of West Kazakhstan region will be determined.

6. Seasonal and age-related dynamics of piroplasmosis in cattle will be determined in various zones of West Kazakhstan region using the PCR method.

7. Comparative assessment of the effectiveness of the medication used against bovine piroplasmosis using PCR in the steppe, semi-desert and desert zones of West Kazakhstan region will be given.

8. Effectiveness of acaricides used against ixodid ticks using invitro and invivo methods will be determined.

9. Rational scheme will be developed and recommendations will be prepared for the prevention of piroplasmosis and ixodidosis in cattle in West Kazakhstan region.

Degree of implementation: no

List of published works within the framework of the project: (with indication of DOI, ISBN) 

Кармалиев Р.С., Сидихов Б.М., Усенов Ж.Т., Нуржанова Ф.Х., Майканов Н.С., Арисов М.В., Сенгалиев Е.М. Иксодиды крупного рогатого скота в Западно-Казахстанской области, видовой состав и распространение // Наука и образование» Научно-практический журнал Западно-Казахстанского аграрно-технического университета имени Жангир хана Уральск. 2024. Т.1. № 3-1 (76), С. 41-54. DOI 10.52578/2305-9397-2024-3-1-41-54